Table 1 Baseline characteristics and 28-day mortality according to the tertiles of the MAP (mmHg) (n = 8161).
Parameters | MAP tertile | |||
|---|---|---|---|---|
Tertile 1 40–56 n = 2545 | Tertile 2 57–110 n = 2848 | Tertile 3 111–200 n = 2768 | P value | |
Demographics | ||||
Age (years) | 69.26 ± 12.92 | 64.80 ± 13.33 | 64.85 ± 13.35 | < 0.001 |
Sex | ||||
Male | 1114 (43.79%) | 870 (30.55%) | 991 (35.80%) | < 0.001 |
Female | 1430 (56.21%) | 1978 (69.45%) | 1777 (64.20%) | |
Ethnicity | ||||
Caucasian | 2071 (82.51%) | 2219 (79.36%) | 2090 (76.28%) | < 0.001 |
African American | 439 (17.49%) | 577 (20.64%) | 650 (23.72%) | |
BMI | 28.70 ± 6.88 | 28.78 ± 5.85 | 29.59 ± 6.47 | < 0.001 |
Vital signs | ||||
Temperature (°C) | 36.38 ± 0.60 | 36.48 ± 0.45 | 36.44 ± 0.54 | < 0.001 |
Respiratory rate (bpm) | 23.51 ± 14.00 | 23.29 ± 14.57 | 26.42 ± 15.57 | < 0.001 |
Heart rate (/min) | 95.19 ± 33.46 | 86.29 ± 28.51 | 91.67 ± 31.74 | < 0.001 |
Laboratory data | ||||
BUN (mg/dL) | 26.90 ± 17.21 | 20.86 ± 13.81 | 21.78 ± 14.01 | < 0.001 |
Calcium (mg/dl) | 8.32 ± 0.74 | 8.53 ± 0.60 | 8.56 ± 0.63 | < 0.001 |
Glucose (mg/dl) | 151.38 ± 62.54 | 139.76 ± 54.10 | 148.88 ± 60.21 | < 0.001 |
Serum potassium (mmol/L) | 4.17 ± 0.61 | 4.09 ± 0.51 | 4.09 ± 0.57 | < 0.001 |
Platelets (cells × 109/L) | 205.16 ± 76.14 | 208.62 ± 70.12 | 214.28 ± 71.52 | < 0.001 |
Red blood cell count (M/mcl) | 3.87 ± 0.72 | 4.15 ± 0.67 | 4.21 ± 0.70 | < 0.001 |
Hemoglobin (g/dL) | 11.58 ± 2.22 | 12.47 ± 2.12 | 12.60 ± 2.21 | < 0.001 |
White blood cell count (cells × 109/L) | 12.74 ± 6.02 | 11.41 ± 4.61 | 11.93 ± 5.11 | < 0.001 |
Sodium (mmol/L) | 137.62 ± 4.24 | 137.70 ± 3.65 | 137.76 ± 3.76 | 0.461 |
CK (units/L) | 1219.48 ± 2319.21 | 1066.49 ± 1704.70 | 1362.19 ± 2451.59 | 0.009 |
HDLc (mg/dL) | 39.43 ± 13.23 | 39.24 ± 11.97 | 40.58 ± 12.83 | 0.015 |
Severity of illness | ||||
GCS score | 13.05 ± 3.61 | 14.38 ± 2.05 | 13.75 ± 3.06 | < 0.001 |
Apache IV score | 62.08 ± 23.20 | 41.31 ± 18.35 | 46.34 ± 22.88 | < 0.001 |
Acute Physiology Score III | 47.68 ± 20.85 | 29.68 ± 15.90 | 34.34 ± 20.25 | < 0.001 |
Comorbidities | ||||
COPD | 225 (8.84%) | 146 (5.13%) | 153 (5.53%) | < 0.001 |
CHF | 411 (16.15%) | 300 (10.53%) | 321 (11.60%) | < 0.001 |
DM | 445 (17.49%) | 368 (12.92%) | 381 (13.76%) | < 0.001 |
Pneumonia | 349 (13.71%) | 174 (6.11%) | 213 (7.70%) | < 0.001 |
Rhythm | 560 (22.00%) | 420 (14.75%) | 467 (16.87%) | < 0.001 |
Advanced life support | ||||
Intubated | 482 (18.94%) | 170 (5.97%) | 311 (11.24%) | < 0.001 |
Mechanical ventilation use | 653 (25.66%) | 269 (9.45%) | 455 (16.44%) | < 0.001 |
DIALYSIS | 92 (3.61%) | 46 (1.62%) | 65 (2.35%) | < 0.001 |
28-day mortality | ||||
No | 2262 (88.88%) | 2778 (97.54%) | 2623 (94.76%) | 0.107 |
Yes | 283 (11.12%) | 70 (2.46%) | .24%) | |