Fig. 4

Molecular visualization of sitosterol _1KZN interaction. (A) showed zoom out of sitosterol (cyan) interacting and clustered to the same binding site of the co crystalized ligand clorobiocin (green) within the active site of DNA-gyrase with PDB ID 1KZN. (B) showed zoom in of sitosterol interacting to the same binding site of clorobiocin. (C) 2D map of sitosterol interacting to crucial amino acids of the active site. (D) Grid visualization showing their overall electrostatic complementary to the active site.