Fig. 7

Molecular visualization of vitexin _3SRW interaction. (A) showed zoom out of vitexin (yellow) interacting and clustered to the same binding site of the co crystalized ligand 7-aryl-2,4-diaminoquinazolines (green) within the active site of DHFR with PDB ID 3SRW. (B) showed zoom in of vitexin interacting to the same binding site of 7-aryl-2,4-diaminoquinazolines. (C) 2D map of vitexin interacting to the crucial amino acids of the active site. (D) Grid visualization showing their overall electrostatic complementary to the active site.