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Research on multi-stage deep learning based intelligent diagnosis of skin diseases and skin medicine diagnosis community construction concept
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  • Published: 22 May 2026

Research on multi-stage deep learning based intelligent diagnosis of skin diseases and skin medicine diagnosis community construction concept

  • Junzhang Chen1,
  • Fapeng Cai2,
  • Weizhe Ding3 &
  • …
  • Dong Liang4 

Scientific Reports (2026) Cite this article

We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Computational biology and bioinformatics
  • Diseases
  • Health care
  • Mathematics and computing
  • Medical research

Abstract

Accurate diagnosis and assessment of the severity of skin diseases are essential for appropriate clinical treatment. This paper proposes a multi-stage intelligent diagnosis framework based on deep learning to assist dermatologists in decision-making. The framework firstly adopts LeNet-5 convolutional neural network for preliminary classification of common skin diseases, and then performs secondary classification of disease severity and progression for selected representative conditions. Through manual annotation, clinical prior knowledge, including the predilectable location of the lesion, is incorporated into the framework to improve the reliability of the diagnosis. All images were preprocessed with grayscale conversion to reduce visual variability. Experimental results show that the performance of the proposed framework is stable and reliable, especially in the recognition tasks of disease severity and stage with obvious clinical manifestations. This hierarchical diagnostic strategy is consistent with routine clinical workflows and shows potential as an adjunct to precision diagnosis and treatment planning in dermatology.

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Acknowledgements

This study was especially grateful to engineer Xinyu Li for his assistance in revising the manuscript, to Dr. Yuliang Hu (Dermatology) for his diagnostic suggestions and patient imaging data, and to Dr. Liu, an anonymous physician from a clinic in Neijiang, Sichuan for his support.

Funding

This work was no funding.

Author information

Authors and Affiliations

  1. Yinshan Town Convenience Service Center, Neijiang, 641000, Sichuan, China

    Junzhang Chen

  2. Neijiang Educational Technology Equipment Guidance Center, Neijiang, 641000, Sichuan, China

    Fapeng Cai

  3. Neijiang Big Data center, Neijiang, 641000, Sichuan, China

    Weizhe Ding

  4. Neijiang Food and Drug Inspection and Testing Center, Neijiang, 641000, Sichuan, China

    Dong Liang

Authors
  1. Junzhang Chen
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  2. Fapeng Cai
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  3. Weizhe Ding
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  4. Dong Liang
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Corresponding author

Correspondence to Fapeng Cai.

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Conflict of interest

The authors declared that we have no conflicts of interest to this work.

Ethical approval

The study protocol was approved by the Institutional Ethics Committee (approval number: NJYY-LL-2026-0228). Patient-related image data were anonymized to protect personal privacy.

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Cite this article

Chen, J., Cai, F., Ding, W. et al. Research on multi-stage deep learning based intelligent diagnosis of skin diseases and skin medicine diagnosis community construction concept. Sci Rep (2026). https://doi.org/10.1038/s41598-026-53742-7

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  • Received: 10 March 2026

  • Accepted: 14 May 2026

  • Published: 22 May 2026

  • DOI: https://doi.org/10.1038/s41598-026-53742-7

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Keywords

  • Diagnosis of skin diseases
  • Deep learning
  • Grading of severity
  • Clinical decision support
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