Table 2 Odronextamab response summary according to ICR

From: Odronextamab monotherapy in patients with relapsed/refractory diffuse large B cell lymphoma: primary efficacy and safety analysis in phase 2 ELM-2 trial

Outcome

ICR (N = 127)

Best overall response, n (%)

 Objective response

66 (52.0)

(95% CI: 42.9–60.9)

 CR

40 (31.5)

(95% CI: 23.5–40.3)

 PR

26 (20.5)

(95% CI: 13.8–28.5)

DOR, median, months

10.2

(95% CI: 5.0–17.9)

 Probability of maintaining objective response at 12 months, %

48.1

(95% CI: 35.1–59.9)

 Probability of maintaining objective response at 24 months, %

36.9

(95% CI: 24.2–49.6)

Duration of CR, median, months

17.9

(95% CI: 10.2–NE)

 Probability of maintaining CR at 12 months, %

61.5

(95% CI: 44.4–74.8)

 Probability of maintaining CR at 24 months, %

47.2

(95% CI: 29.7–62.9)