Fig. 3: A maximum likelihood tree constructed using IQ-Tree 223 with the HKY substitution model34. | Communications Medicine

Fig. 3: A maximum likelihood tree constructed using IQ-Tree 223 with the HKY substitution model34.

From: First imported cases of MPXV Clade Ib from Goma, Democratic Republic of the Congo

Fig. 3: A maximum likelihood tree constructed using IQ-Tree 223 with the HKY substitution model34.The alternative text for this image may have been generated using AI.

We included a Clade Ia genome as an outgroup and then removed it after rooting. Single-nucleotide mutations are reconstructed and displayed, denoting whether they are APOBEC3-mediated (red bars) or other mutations (blue bars). Genomes from recent cases in Goma, North Kivu, are denoted with yellow circles. Patients 1 and 2 each have multiple genomes sequenced from different samples. Blue circles are genomes from Kamituga, South Kivu, from October and December 2023, and January 2024. Letters in parentheses are referenced in Table 2.

Back to article page