Fig. 3: Single cell clustering analysis. | BJC Reports

Fig. 3: Single cell clustering analysis.

From: Whole genome sequencing and single-cell transcriptomics identify KMT2D inactivation as a potential new driver for pituitary tumors: a case report

Fig. 3: Single cell clustering analysis.The alternative text for this image may have been generated using AI.

a Initial clustering with 13 clusters. b Annotated UMAP based on canonical markers and automated annotation pipeline. c Copykat heatmap representing chromosomal alterations. Blue for deletion and orange for amplification. Y axis bar represent predicted aneuploid and diploid cells. d Quantification of KMT2D-expressing cells across PitNET samples with paired scRNA-seq and WGS data, compared to healthy control tissue.

Back to article page