Table 1 Cohort characteristics by family history

From: Family history of premature CHD and risk factor control in patients with a recent ACS

Characteristics

N

Overall, N = 1423a

FHx, N = 556a

No FHx, N = 867a

p valueb

Age

1423

58 (10.67)

56 (10.83)

59 (10.44)

<0.001

Gender

1423

   

<0.001

 Male

 

1,127 (79.20%)

407 (73.20%)

720 (83.04%)

 

 Female

 

296 (20.80%)

149 (26.80%)

147 (16.96%)

 

Ethnicity

1423

   

<0.001

 Caucasian

 

1138 (79.97%)

435 (78.24%)

703 (81.08%)

 

 Aboriginal/Torres Strait Islander

 

52 (3.65%)

37 (6.65%)

15 (1.73%)

 

 Asian

 

127 (8.92%)

40 (7.19%)

87 (10.03%)

 

 Arab or Persian

 

38 (2.67%)

16 (2.88%)

22 (2.54%)

 

 Otherc

 

68 (4.78%)

28 (5.04%)

40 (4.61%)

 

BMI

1408

29 (5.48)

30 (5.80)

29 (5.25)

0.028

Smoker

1423

378 (26.56%)

160 (28.78%)

218 (25.14%)

0.146

≥10 standard drinks per week

1421

298 (20.97%)

108 (19.46%)

190 (21.94%)

0.292

Employment status

1421

   

0.003

 Employed

 

853 (60.03%)

348 (62.70%)

505 (58.31%)

 

 Unemployed

 

178 (12.53%)

81 (14.59%)

97 (11.20%)

 

 Retired

 

390 (27.45%)

126 (22.70%)

264 (30.48%)

 

Education status

1419

   

0.868

 Year 10 and below

 

510 (35.94%)

203 (36.58%)

307 (35.53%)

 

 Year 12 (Higher School Certificate)

 

242 (17.05%)

96 (17.30%)

146 (16.90%)

 

 University/Diploma

 

667 (47.00%)

256 (46.13%)

411 (47.57%)

 

Marital Status

1423

   

0.168

 Single

 

217 (15.25%)

101 (18.17%)

116 (13.38%)

 

 Married

 

855 (60.08%)

318 (57.19%)

537 (61.94%)

 

 Separated

 

178 (12.51%)

69 (12.41%)

109 (12.57%)

 

 Widowed

 

64 (4.50%)

26 (4.68%)

38 (4.38%)

 

 Defacto

 

109 (7.66%)

42 (7.55%)

67 (7.73%)

 

Income Status

1420

   

0.045

 Less than $999 per week/$51,999 per year

 

447 (31.48%)

193 (34.84%)

254 (29.33%)

 

 More than $999 per week/$51,999 per year

 

574 (40.42%)

222 (40.07%)

352 (40.65%)

 

 No response

 

399 (28.10%)

139 (25.09%)

260 (30.02%)

 

Physical disability

1423

67 (4.71%)

28 (5.04%)

39 (4.50%)

0.735

Prior cardiovascular events

1423

444 (31.20%)

170 (30.58%)

274 (31.60%)

0.727

Myocardial infarction locationd

 Left Main Coronary

1346

67 (4.98%)

31 (5.87%)

36 (4.40%)

0.226

 Left Anterior Descending

1346

855 (63.52%)

337 (63.83%)

518 (63.33%)

0.852

 Left Circumflex

1346

536 (39.82%)

212 (40.15%)

324 (39.61%)

0.843

 Right Coronary

1346

713 (52.97%)

284 (53.79%)

429 (52.44%)

0.630

Received texts in TEXTMEDS study

1423

715 (50.25%)

291 (52.34%)

424 (48.90%)

0.226

Systolic BP (mmHg)

1420

123 (15.72)

123 (15.31)

123 (15.98)

0.857

Diastolic BP (mmHg)

1420

73 (10.13)

73 (9.80)

73 (10.34)

0.246

LDL-C (mmol/L)

1232

3 (1.09)

3 (1.11)

3 (1.08)

0.271

HDL-C (mmol/L)

1273

1 (0.41)

1 (0.31)

1 (0.46)

0.092

Total cholesterol (mmol/L)

1320

5 (1.36)

5 (1.37)

5 (1.35)

0.028

Triglyceride (mmol/L)

1315

2 (1.85)

2 (2.36)

2 (1.40)

0.004

Number of antihypertensives prescribed on discharge

1423

   

0.509

 0

 

87 (6.11%)

36 (6.47%)

51 (5.88%)

 

 1

 

374 (26.28%)

137 (24.64%)

237 (27.34%)

 

 2

 

962 (67.60%)

383 (68.88%)

579 (66.78%)

 

Prescribed statin/lipid-lowering agent on discharge

1423

1,386 (97.40%)

539 (96.94%)

847 (97.69%)

0.485

Hypertension

1423

680 (47.79%)

273 (49.10%)

407 (46.94%)

0.459

Diabetes

1423

340 (23.89%)

145 (26.08%)

195 (22.49%)

0.138

Obesity

1408

544 (38.64%)

246 (44.65%)

298 (34.77%)

<0.001

Hyperlipidaemia

1423

709 (49.82%)

293 (52.70%)

416 (47.98%)

0.093

Sleep apnoea

1423

154 (10.82%)

78 (14.03%)

76 (8.77%)

0.002

History of depression

1423

265 (18.62%)

125 (22.48%)

140 (16.15%)

0.003

Chronic kidney disease

1422

37 (2.60%)

12 (2.16%)

25 (2.88%)

0.507

SF12 quality of life physical health score

1423

25 (6.36)

25 (6.99)

26 (5.88)

0.001

SF12 quality of life mental health score

1423

13 (3.17)

13 (3.53)

13 (2.91)

0.007

Anxiety

828

116 (14.01%)

53 (16.31%)

63 (12.52%)

0.153

Exercising regularly

1415

902 (63.75%)

353 (63.83%)

549 (63.69%)

>0.999

Adherence to beta blockers at 6/12 monthse

1193

1001 (83.91%)

390 (83.33%)

611 (84.28%)

0.725

Adherence to ACEi/ARB at 6/12 monthse

1256

986 (78.50%)

387 (79.47%)

599 (7.89%)

0.555

Adherence to statins at 6/12 monthse

1322

1255 (94.93%)

478 (93.73%)

777 (95.69%)

0.145

  1. Bold values indicates statistical significance at 5% (p ≤ 0.05).
  2. FHx family history, BMI body mass index, BP blood pressure, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, SF12 12-item Short Form Survey, ACEi Angiotensin-converting enzyme inhibitor, ARB Angiotensin receptor blocker, SD standard deviation.
  3. aMean (SD); n (%).
  4. bWelch Two Sample t-test; Pearson’s Chi-squared test.
  5. cIncludes Black African and Coloured African (Sub-Saharan Africa).
  6. dInfarction location defined by stenosis greater than 50% in the specified vessel.
  7. eAdherence is defined as > 80% adherent to the particular medication at both the 6- and 12-month follow-up.