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Advanced filters: Author: Abigail Bojanowski Clear advanced filters

  • Chemical modification of mRNA nucleobases alters hydrogen bonding during translation. Here the authors show that the N1-methylpseudouridine (m1ψ), used in therapeutics, does not change translation rate but modestly modulates its fidelity in a codon-position and tRNA dependent manner.

    • Jeremy Monroe
    • Daniel E. Eyler
    • Kristin S. Koutmou
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11