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Showing 1–2 of 2 results
Advanced filters: Author: Alfred Hanswillemenke Clear advanced filters

  • Hanswillemenke, Hofacker and colleagues developed a proximity labeling-based method to identify protein interactome of small molecules and RNA drugs within living cells, facilitating the design and development of RNA drugs with enhanced pharmacological properties.

    • Alfred Hanswillemenke
    • Daniel Tobias Hofacker
    • Thorsten Stafforst
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 20, P: 555-565

  • RNA base editing enables a precise, reversible and doseable change of genetic information. Here, authors propose base editing as a method to control post-translational modifications via removal of regulatory phosphorylation and acetylation sites, applying the approach to modulation of the JAK/STAT pathway via editing of wildtype alleles.

    • Karthika Devi Kiran Kumar
    • Shubhangi Singh
    • Thorsten Stafforst
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16