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Showing 1–2 of 2 results
Advanced filters: Author: Daniel Tobias Hofacker Clear advanced filters

  • Hanswillemenke, Hofacker and colleagues developed a proximity labeling-based method to identify protein interactome of small molecules and RNA drugs within living cells, facilitating the design and development of RNA drugs with enhanced pharmacological properties.

    • Alfred Hanswillemenke
    • Daniel Tobias Hofacker
    • Thorsten Stafforst
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 20, P: 555-565

  • RNA base editing represents an exciting modality in precision genetic medicine. Here the authors develop short, metabolically stable RNA oligonucleotides (RESTORE 2.0) that enable precise and efficient RNA base editing, demonstrating successful in-vivo correction of a disease-causing human mutation.

    • Laura S. Pfeiffer
    • Tobias Merkle
    • Thorsten Stafforst
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15