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Advanced filters: Author: Iris Lodewijk Clear advanced filters

CD44v6 is associated with tumor aggressiveness and chemoresistance in bladder cancer

Iris Lodewijk
Carolina Rubio
Marta Dueñas
ResearchOpen Access11 Mar 2026
Scientific Reports

Volume: 16, P: 1-20
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer

Mismatch repair-deficient colorectal cancer clones adapt their mutation landscape by toggling homopolymer sequences in MutS homolog 3 (MSH3) and MutS homolog 6 (MSH6). This increases the subclonal mutation rate and clonal diversity, favoring immune escape and tumor growth.

Hamzeh Kayhanian
William Cross
Marnix Jansen
ResearchOpen Access03 Jul 2024
Nature Genetics

Volume: 56, P: 1420-1433
Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression

Inhibition of histone and DNA methyltransferase activity enhances sensitivity to platinum-based and immunotherapy in a novel transgenic mouse model of metastatic bladder cancer.

Cristina Segovia
Edurne San José-Enériz
Jesús M. Paramio
Research03 Jul 2019
Nature Medicine

Volume: 25, P: 1073-1081
Modulation of tumor microenvironment by targeting histone acetylation in bladder cancer

Sandra P. Nunes
Lucia Morales
Jesús M. Paramio
ResearchOpen Access04 Jan 2024
Cell Death Discovery

Volume: 10, P: 1-15
Antisense oligonucleotide-mediated exon skipping as a strategy to reduce proteolytic cleavage of ataxin-3

Lodewijk J. A. Toonen
Iris Schmidt
Willeke M. C. van Roon-Mom
ResearchOpen Access12 Oct 2016
Scientific Reports

Volume: 6, P: 1-11