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Showing 1–3 of 3 results
Advanced filters: Author: Juliette Fedry Clear advanced filters
  • Structural studies of the ribosome-associated endoplasmic reticulum translocon complex based on cryo-electron tomography and molecular modelling reveal multiple intermediate states and interactions between the components of the complex and its cofactors.

    • Max Gemmer
    • Marten L. Chaillet
    • Friedrich Förster
    ResearchOpen Access
    Nature
    Volume: 614, P: 160-167
  • HAP2 is essential for gamete fusion during fertilization and is conserved among eukaryotes. Here the authors show that species-specific adhesion between Chlamydomonas plus and minus gametes initiates HAP2 to undergo a fusogenic conformational change into homotrimers via a molecular mechanism akin to that of enveloped viruses.

    • Jun Zhang
    • Jennifer F. Pinello
    • William J. Snell
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12