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Advanced filters: Author: Katherine N. Theken Clear advanced filters

  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) have been associated with adverse effects affecting both the cardiovascular and gastrointestinal systems. Here the authors show that NSAIDs lower plasma tryptophan concentrations in humans and mice and that replacement of tryptophan in mice treated with naproxen leads to decreased adverse effects.

    • Soumita Ghosh
    • Nicholas F. Lahens
    • Garret A. FitzGerald
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-16