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Showing 1–2 of 2 results
Advanced filters: Author: Kayla A. Kruger Clear advanced filters

  • Variants in the PSMC5 gene impair proteasome function and cellular homeostasis, altering brain development in children. This study reveals underlying molecular mechanisms contributing to this neurodevelopmental phenotype, and suggests therapeutic leads for neurodevelopmental proteasomopathies.

    • Sébastien Küry
    • Janelle E. Stanton
    • Elke Krüger
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-21

  • Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.

    • Nitsan Goldstein
    • Amadeus Maes
    • J. Nicholas Betley
    ResearchOpen Access
    Nature
    Volume: 647, P: 689-697