Nature Search

Clinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy

Guadalupe A. Cifuentes
Adrián Santiago
Rubén Cabanillas
ResearchOpen Access22 Dec 2022
British Journal of Cancer

Volume: 128, P: 857-876
Intravenous administration of BCG in mice promotes natural killer and T cell-mediated antitumor immunity in the lung

Intravesical administration of BCG is a standard treatment for bladder cancer. In this study, the authors examine the effect of systemic BCG administration in murine models of primary lung cancer and melanoma metastasis, demonstrating a beneficial effect either alone or in combination with PD-L1.

Eduardo Moreo
Aitor Jarit-Cabanillas
Nacho Aguiló
ResearchOpen Access04 Oct 2023
Nature Communications

Volume: 14, P: 1-17
BRAF v600E–mutant cancers treated with vemurafenib alone or in combination with everolimus, sorafenib, or crizotinib or with paclitaxel and carboplatin (VEM-PLUS) study

Blessie Elizabeth Nelson
Jason Roszik
Vivek Subbiah
ResearchOpen Access18 Feb 2023
npj Precision Oncology

Volume: 7, P: 1-13
Next-generation sequencing for identification of actionable gene mutations in intestinal-type sinonasal adenocarcinoma

Paula Sánchez-Fernández
Cristina Riobello
José Luis Llorente
ResearchOpen Access26 Jan 2021
Scientific Reports

Volume: 11, P: 1-10
Genomic alterations in thyroid cancer: biological and clinical insights

Genomic data from patients with thyroid cancer, combined with information on mutation-specific mechanisms from experimental models, is transforming the thyroid cancer research field. This Review summarizes the genetic alterations involved in follicular cell-derived thyroid cancer initiation and progression and their biological and clinical implications.

Iñigo Landa
Maria E. Cabanillas
Reviews04 Dec 2023
Nature Reviews Endocrinology

Volume: 20, P: 93-110
Adaptive Darwinian off-target resistance mechanisms to selective RET inhibition in RET driven cancer

Vivek Subbiah
Mohamed A. Gouda
Jie Wu
ResearchOpen Access04 Mar 2024
npj Precision Oncology

Volume: 8, P: 1-9
Radixin modulates the function of outer hair cell stereocilia

Sonal Prasad et al. identify several mutations in the radixin (RDX) gene that are associated with early-life hearing loss. Using a guinea pig model, they propose that radixin helps convert sound into electrical signals in the mature inner ear.

Sonal Prasad
Barbara Vona
Anders Fridberger
ResearchOpen Access23 Dec 2020
Communications Biology

Volume: 3, P: 1-15
Evolutionary adaptation of an RNA bacteriophage to the simultaneous increase in the within-host and extracellular temperatures

Ester Lázaro
María Arribas
Esther Acosta
ResearchOpen Access24 May 2018
Scientific Reports

Volume: 8, P: 1-9

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