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Showing 1–3 of 3 results
Advanced filters: Author: Symone V. Jordan Clear advanced filters

  • Analyses of the association between fatty acids and prostate cancer have often neglected African patients. Here, the authors analyse 24 circulating fatty acids in Ghanaian, African American, and European American men, and explore the associations with socio-demographic factors, diet, FADS1/2 locus, and prostate cancer.

    • Tsion Zewdu Minas
    • Brittany D. Lord
    • Stefan Ambs
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16

  • Ancestry-related differences in immunobiology may explain the health disparities observed in prostate cancer patients, with men of African origin bearing the highest prostate cancer burden. By measuring immune-related proteins in serum samples, here the authors report that systemic cytokines linked to suppression of tumor immunity are upregulated in men of African ancestry and associated with reduced survival.

    • Tsion Zewdu Minas
    • Julián Candia
    • Stefan Ambs
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14

  • Tsion Zewdu Minas et al. find that men carrying an IFNL4 variant that is more common in African Americans and is associated with impaired viral clearance have a higher risk of prostate cancer. Specifically, this risk is increased in IFNL4 variant carriers with more lifetime sexual partners, suggesting a link to impaired clearance of sexually transmitted infections

    • Tsion Zewdu Minas
    • Wei Tang
    • Stefan Ambs
    ResearchOpen Access
    Communications Biology
    Volume: 1, P: 1-10