Chiara de Lucia et al. investigate the relationships between genetic variants of nutrient-sensing gene candidates and their association with lifestyle factors and cognitive performance in a human cohort and the expression levels of those genes in in vitro model systems. They find that ABTB1 and GRB10 are key genes involved in aging, lifestyle, and cognitive performance.
- Chiara de Lucia
- Tytus Murphy
- Sandrine Thuret