Table 2 Expression Levels of CD46, CD55, CD59, HLA Class I, G250, and Ep-CAM on Cervical Carcinoma Cell Lines (CCCL) and Normal Cervix Epithelial Cell Cultures

From: The Inhibitory Effect of CD46, CD55, and CD59 on Complement Activation After Immunotherapeutic Treatment of Cervical Carcinoma Cells with Monoclonal Antibodies or Bispecific Monoclonal Antibodies

CCCL

CD46

CD55

CD59

HLA Cl. I

Na

G250

N

Ep-CAM

N

HeLa

46 ± 15b

159 ± 50

157 ± 41

823 ± 158

7

5 ± 5

7

20 ± 11

4

SiHa

59 ± 8

63 ± 14

177 ± 49

486 ± 86

6

5 ± 5

7

8 ± 2

3

CaSki

77 ± 9

36 ± 16

377 ± 74

615 ± 15

3

9 ± 1

2

92 ± 16

3

CSCC1

34 ± 10

29 ± 4

275 ± 28

123 ± 32

3

0 ± 0

3

45 ± 16

3

CSCC7

16 ± 2

22 ± 2

122 ± 82

45 ± 9

3

0 ± 0

4

14 ± 3

2

CC8

53 ± 29

26 ± 6

170 ± 51

128 ± 35

6

0

1

6 ± 4

3

CC10A

91 ± 31

44 ± 22

548 ± 140

160 ± 65

4

0 ± 1

3

63 ± 7

3

CC10B

46 ± 23

17 ± 4

220 ± 99

130 ± 28

4

61 ± 23

2

38 ± 4

2

CC11+

34 ± 12

21 ± 11

157 ± 56

122 ± 79

6

0

0

112 ± 58

4

NCE1c

35

4

580

220

1

13 ± 18

4

n.d.

0

NCE2

29 ± 15

3 ± 2

532 ± 319

312 ± 62

2

n.d.

2

4 ± 2

2

  1. Expression levels were determined by flow cytometry as described in “Material and Methods.”
  2. Number of experimental values used.
  3. bMESF values (×104) ± SD.
  4. NCE, normal cervical epithelium.
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