Figure 4
From: Gene Transfer of IκBα Limits Infarct Size in a Mouse Model of Myocardial Ischemia-Reperfusion Injury
Electrophoretic mobility shift assay (EMSA) of NF-κB in mice myocardium. Samples were normal myocardium of sham-operated mice (Sham MI/R; A) and myocardium-at-risk of mice subjected to MI/R injury and treated with PBS (B), rAAV-LacZ (C), or rAAV-IκBα (D). (Top) Representative EMSA picture highlighting NF-κB binding activity. (Bottom) Quantitative data and integrated intensity of NF-κB binding activity. Each point represents the mean ± sd of seven experiments. *p < 0.01 versus the corresponding basal value; §p < 0.05 versus time 1 hour; #p < 0.05 versus rAAV-LacZ.
