Table 1 Serum Creatinine Phosphokinase (U/100 ml) Activity and Myocardial ELA activity (μg/gm tissue) in MI/R

From: Gene Transfer of IκBα Limits Infarct Size in a Mouse Model of Myocardial Ischemia-Reperfusion Injury

Treatment

Serum creatinine phosphokinase (U/100 ml)

Myocardial ELA activity (μg/g tissue)

 

End of occlusion

End of reperfusion

Nonischemic myocardium

AAR

Infarct area

Sham MI/R + rAAV-LacZ

232 ± 11

228 ± 14

0.22 ± 0.03

—

—

Sham MI/R + rAAV-IκBα

235 ± 10

241 ± 17

0.26 ± 0.04

—

—

MI/R + PBS

219 ± 15

225 ± 13

0.25 ± 0.05

2.4 ± 0.5

2.7 ± 0.2

MI/R + rAAV-LacZ

220 ± 16

1983 ± 25

0.27 ± 0.03

2.5 ± 0.4

2.9 ± 0.6

MI/R + rAAV-IκBα

231 ± 18

835 ± 14a

0.29 ± 0.06

0.6 ± 0.05*

0.4 ± 0.02a

  1. Each point represents the mean ± SD of seven experiments.
  2. p < 0.01 vs MI/R + rAAV-LacZ.
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