Figure 2 | Modern Pathology

Figure 2

From: Ultrasound-accelerated formalin fixation of tissue improves morphology, antigen and mRNA preservation

Figure 2

Comparison of the preservation of morphological details in brain tissues undergoing conventional 16- to 24-h overnight fixation, and 10–15 min of ultrasound fixation. Fixed tissues are subject to 16–18 h of automated tissue processing. H&E-stained sections indicated better morphologic characteristics in ultrasound-fixed tissue (b) than in conventionally fixed tissue (a). Original magnification × 400. Immunohistochemistry detection with NFP antibody indicated stronger immunohistochemistry staining and less neuron fiber fragmentation in ultrasound-fixed tissue (d) than in conventionally fixed tissue (c). Original magnification × 100.

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