Figure 2 | Modern Pathology

Figure 2

From: Dense deposit disease is not a membranoproliferative glomerulonephritis

Figure 2

Dense deposit disease, distinctive features by light microscopy. (a) Strongly PAS-positive ‘ribbons’ along glomerular basement membranes × 400 PAS. (b) Thioflavin T positive in glomerular basement membranes and Bowman's capsule basement membranes, × 400 thioflavin T. (c) Toluidine blue stain intermittently accentuated in glomerular basement membranes and Bowman's capsule basement membranes (normal area single arrowhead, accentuated area double arrowhead, boxed area shown at higher magnification in d), × 600 toluidine blue. (d) High power of toluidine blue stained area of Bowman's capsule showing normal basement membrane thickness and density (single arrowhead) and accentuated basement membrane (double arrowhead), × 1200 toluidine blue.

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