TABLE 1 Morphologic Characteristics of the First Positive HCV RNA Post-Transplant Biopsy Specimen by RT-PCR

From: Early Detection of Hepatitis C Allograft Reinfection after Orthotopic Liver Transplantation: A Molecular and Histologic Study

Case

HCV RNA First positive biopsy

Reader No.

mHAI (25)

Steatosis

Morphologic Impression

   

A

B

C

D

  

1

1 yr

1

0

0

0

0

Minimal

No recurrent HCV

  

2

0

0

0

0

Absent

 

2

3 wk

1

0

0

1

0

Absent

No recurrent HCV

  

2

0

3

1

0

Absent

 

3

4 wk

1

0

0

2

0

Absent

Indeterminate HCV, lobular

  

2

0

0

1

0

Absent

 

4

8 days

1

0

0

2

0

Absent

HCV, lobular

  

2

0

0

2

0

Absent

 

5

9 days

1

1

0

0

1

Absent

Indeterminate HCV, periportal

  

2

0

0

0

0

Absent

 

6

3 wk

1

1

0

1

0

Minimal

Indeterminate HCV, lobular

  

2

0

0

0

0

Absent

 

7

4 wk

1

0

0

0

0

Absent

No recurrent HCV

  

2

0

0

0

0

Absent

 

8

8 days

1

0

0

1

0

Absent

Indeterminate HCV, lobular

  

2

0

0

1

1

Absent

 

9

7 days

1

0

0

0

1

Minimal

No recurrent HCV

  

2

0

0

1

1

Absent

 

10

3 yr

1

0

0

0

0

Moderate

No-recurrent HCV

  

2

0

0

0

0

Mild

 

11

3 wk

1

0

0

0

0

Absent

No-recurrent HCV

  

2

0

0

0

1

Absent

 

12

4 wk

1

0

0

0

0

Absent

No recurrent HCV

  

2

0

0

1

0

Absent

 

13

7 days

1

0

0

1

0

Absent

Indeterminate HCV, lobular

  

2

0

0

1

0

Absent

 

14

5 days

1

1

0

1

0

Absent

HCV, periportal

  

2

1

0

1

2

Absent

 
  1. PHCV, hepatitis C virus; RT-PCR, reverse transcriptase-polymerase chain reaction; mHAI, modified hepatic activity index.