FIGURE 1 | Modern Pathology

FIGURE 1

From: Telomerase Activity Significantly Correlates with Chromosome Alterations, Cell Differentiation, and Proliferation in Lung Adenocarcinomas

FIGURE 1

Telomerase activity in lung adenocarcinomas by the telomeric repeat amplification protocol assay. Extracts from SiHa cells (as a positive control) were analyzed as an internal telomerase standard. Lane 1, 103 SiHa cells with positive telomerase activity; lane 2, lysis buffer (as negative control); lanes 3 and 4, lung adenocarcinoma (T; poorly differentiated type) and noncancer lung tissue (N) from Case 23; lanes 5 and 6, lung adenocarcinoma (T; moderately differentiated type) and noncancer lung tissue (N) from Case 18; lanes 7 and 8, lung adenocarcinoma (T; well-differentiated type) and noncancer lung tissue (N) from Case 8. According to the relative intensity to internal telomerase standard, the telomerase activity was scored as 3, 2, and 1 in lanes 3, 5, and 7, respectively.

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