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Nanotechnology

Carbon nanotubes with DNA recognition

Abstract

Since the discovery of their one-dimensional electronic band structure1, the leading candidate that has emerged for nanodevice applications is single-walled carbon nanotubes (SWNTs) . Here we unite their unique properties with the specific molecular-recognition features of DNA by coupling SWNTs to peptide nucleic acid (PNA, an uncharged DNA analogue2) and hybridizing these macromolecular wires with complementary DNA. Our findings provide a new, versatile means of incorporating SWNTs into larger electronic devices by recognition-based assembly, and of using SWNTs as probes in biological systems by sequence-specific attachment.

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Figure 1: Attachment of DNA to carbon nanotubes.

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Correspondence to Keith A. Williams.

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The authors declare no competing financial interests.

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Williams, K., Veenhuizen, P., de la Torre, B. et al. Carbon nanotubes with DNA recognition. Nature 420, 761 (2002). https://doi.org/10.1038/420761a

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