Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Leslie NR et al. (2004) Biochem J 382: 1–11.
Parsons R (2004) Semin Cell Dev Biol 15: 171–176.
Sansal I et al. (2004) J Clin Oncol 22: 2954–2963.
Lian Z et al. (2005) Oncogene 24: 7394–7400.
Chow LML et al. (2006) Cancer Lett 241: 184–196.
Gericke A et al. (2006) Gene 374: 1–9.
Gimm O et al. (2000) Am J Pathol 156: 1693–1700.
Lachyankar MB et al. (2000) J Neurosc 20: 1404–1413.
Torres J et al. (2001) Eur J Cancer 37: 114–121.
Ginn-Pease ME et al. (2003) Cancer Res 63: 282–286.
Chung JH et al. (2005) Cancer Res 65: 4108–4116.
Liu F et al. (2005) J Cell Biochem 96: 221–234.
Gil A et al. (2006) Mol Biol Cell 17: 4002–4013.
Walker SM et al. (2001) Biochem J 360: 277–283.
Tapparel C et al. (2003) Gene 323: 189–199.
Maehama T et al. (2001) Ann Rev Biochem 70: 247–279.
Campbell RB et al. (2003) J Biol Chem 278: 33617–33620.
McConnachie G et al. (2003) Biochem J 371: 947–955.
Walker SM et al. (2004) Biochem J 379: 301–307.
Torres J et al. (2003) J Biol Chem 278: 30652–30660.
Lee JO et al. (1999) Cell 99: 323–334.
Georgescu MM et al. (2000) Cancer Res 60: 7033–7038.
Vazquez F et al. (2001) J Biol Chem 276: 48627–48630.
Das S et al. (2003) Proc Natl Acad Sci USA 100: 7491–7496.
Sumitomo M et al. (2004) Cancer Cell 5: 67–78.
Vazquez F et al. (2006) Proc Natl Acad Sci USA 103: 3633–3638.
Vazquez F et al. (2006) Cell Cycle 5: 1523–1527.
Okumura K et al. (2006) J Biol Chem 281: 26562–26568.
Crockett DK et al. (2005) Proteomics 5: 1250–1262.
Freeman DJ et al. (2003) Cancer Cell 3: 117–130.
Okumura K et al. (2005) Proc Natl Acad Sci USA 102: 2703–2706.
Tang Y et al. (2006) Cancer Res 66: 736–742.
Li G et al. (2006) Mol Cell 23: 575–587.
Weng L et al. (2001) Hum Mol Genet 10: 599–604.
Radu A et al. (2003) Mol Cell Biol 23: 6139–6149.
Chung JH et al. (2005) Cancer Res 65: 8096–8100.
Liu JL et al. (2005) Mol Cell Biol 25: 6211–6224.
Deleris P et al. (2003) J Biol Chem 278: 38884–38891.
Ahn JY et al. (2004) EMBO J 23: 3995–4006.
Deleris P et al. (2006) J Cell Biochem 98: 469–485.
Trotman LC et al. (2006) Nature 441: 523–527.
Acknowledgements
This work was supported by grants from Ministerio de Ciencia y Tecnología (SAF2002-00085 and BMC2003-02696) (Spain and European Union), Generalitat Valenciana (GV06/036) (Spain), Instituto de Salud Carlos III (CP04/00318) (Spain), and Fundación Mutua Madrileña (Spain). We thank C Romá for his assistance in artwork elaboration.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Gil, A., Andrés-Pons, A. & Pulido, R. Nuclear PTEN: a tale of many tails. Cell Death Differ 14, 395–399 (2007). https://doi.org/10.1038/sj.cdd.4402073
Published:
Issue date:
DOI: https://doi.org/10.1038/sj.cdd.4402073
This article is cited by
-
Hyperphosphorylated PTEN exerts oncogenic properties
Nature Communications (2023)
-
Functional analysis of PTEN variants of unknown significance from PHTS patients unveils complex patterns of PTEN biological activity in disease
European Journal of Human Genetics (2023)
-
Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology
npj Precision Oncology (2019)
-
A pathogenic role for germline PTEN variants which accumulate into the nucleus
European Journal of Human Genetics (2018)
-
Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization
Oncogene (2017)
