Abstract
Proliferative vitreoretinopathy (PVR) remains a difficult management problem despite advances in vitreoretinal surgery. There is still a significant incidence of PVR in rhegmatogenous retinal detachment and other forms of retinal disease. Surgery for PVR now has a high anatomical success rate although visual results are often disappointing. The use of adjunctive treatments to prevent cellular proliferation holds promise for the prevention of PVR or recurrences after surgery. Control of proliferation and strategies aimed at improving visual outcome are important areas of future research in PVR and other forms of retinal disease. Studies of the intraretinal and peri-retinal pathology of PVR have demonstrated characteristic changes which may have a significant influence on visual outcome and surgical management.
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Acknowledgements
This work was supported by grant EY-00888 from the National Eye Institute of the National Institutes of Health; Special Trustees of Moorfields Eye Hospital; The Royal College of Surgeons of Edinburgh & The Royal Blind Asylum/Scottish National Institution for the War Blinded. CS Sethi is a Medical Research Council Clinical Training Fellow. This material were presented at the 31st Cambridge Ophthalmological Symposium, Cambridge, UK.
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Charteris, D., Sethi, C., Lewis, G. et al. Proliferative vitreoretinopathy—developments in adjunctive treatment and retinal pathology. Eye 16, 369–374 (2002). https://doi.org/10.1038/sj.eye.6700194
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DOI: https://doi.org/10.1038/sj.eye.6700194
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