Abstract
Background and purpose Patients are increasingly well informed about the availability of antioxidant products and the claims made for their benefits in age-related macular degeneration (AMD). Consequently, their use is becoming widespread. The purpose of this study is to conduct a survey of the commonly encountered products, and to compare their ingredients with the current Age-Related Eye Disease Study (AREDS) recommendations.
Methods A search was undertaken for products sold as ‘eye nutrients’ at local pharmacies and health food shops, and for products advertised via the Internet. Information about these products was collated and analysed.
Results We identified 22 eye nutrient products. Analysis of their constituents showed that, although over 75% contained all the constituents used in AREDS, only two matched the dosage profiles recommended in the study.
Conclusion The authors draw no conclusion on the efficacy of nutritional supplements in the prevention of AMD. In order to advise their patients, ophthalmologists should be familiar with these products. The compiled list in this paper should provide a useful reference for them.
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References
West S, Vitale S, Hallfrisch J, Munoz B, Muller D, Bressler S et al. Are antioxidants or supplements protective for age related macular degeneration? Arch Ophthalmol 1994; 112: 222–227.
Newsome DA, Swarz M, Leone NC, Elston RC, Miller E . Oral zinc in macular degeneration. Arch Ophthalmol 1988; 106: 192–198.
Holz FG, Wolfensberger TJ, Piguet B, Gross-Jendroska M, Arden GB et al. Oral zinc-therapy in age-related macular degeneration: a double-blind study (abstract). German J Ophthal 1993; 2: 391.
Kaiser HJ, Flammer J, Stumpfig D, Hendrickson P . Visaline in the treatment of age related macular degeneration: a pilot study. Ophthalmologica 1995; 209: 302–305.
Stur M, Tittl M, Reitner A, Meisinger V . Oral zinc and the second eye in age related macular degeneration. Invest Ophthalmol Vis Sci 1996; 37: 1225–1235.
Richer S . Multicenter ophthalmic and nutritional age related macular degeneration study—Part 2: antioxidant intervention and conclusions. J Am Optometry Assoc 1996; 67: 30–49.
Taylor HR, Tikellis G, Robman LD, McCarty CA, McNeil JJ . Vitamin E supplementation and age-related maculopathy (abstract). Invest Ophthalmol Vis Sci 2001; 42: S311.
Taylor HR, Tikellis G, Robman LD, McCarty CA, McNeil JJ . Vitamin E supplementation and macular degeneration: randomised controlled trial. BMJ 2002; 325 (7354): 11.
Smith W, Mitchell P, Webb K, Leeder SR . Dietary antioxidants and age-related maculopathy: the Blue Mountains Eye Study. Ophthalmology 1999; 106: 761–767.
Evans JR . Antioxidant vitamin and mineral supplements for age-related macular degeneration. Cochrane Database Syst Rev 2002 (2): CD000254.
Age Related Eye Disease Study Group. A randomised, placebo-controlled, clinical trial of high-dose supplementation with vitamin C and E, beta carotene, and zinc for age related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthal 2001; 119: 1417–1436.
Bayer consumer care division. One a Day 2001. http://www.bayercare.com/oad/faqgen.html. (accessed 26th February 2003).
Garrow JS, James WPT Human Nutrition and Dietetics, 9th ed. Churchill Livingstone: UK 1998.
National Academy of Science, Food and Nutrition Board. Dietary Reference Intakes Tables 2003. http://www.iom.edu/IOM/IOMHome.nsf/Pages/Food+and+Nutrition+Board. (accessed 25 April 2003).
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Arora, S., Musadiq, M., Mukherji, S. et al. Eye nutrient products for age-related macular degeneration: what do they contain?. Eye 18, 470–473 (2004). https://doi.org/10.1038/sj.eye.6700700
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DOI: https://doi.org/10.1038/sj.eye.6700700
