Abstract
Aim
To report four cases of central retinal vein occlusion (CRVO) in a French family.
Patients and methods
Ophthalmological examination and medical work-up of seven members of the family.
Results
There were four cases of CRVO in two consecutive generations. Three of them had CRVO in both eyes. Arterial hypertension was present in two, associated to glaucoma in one. Medical work-up did not reveal additional risk factors.
Conclusions
We report a case of familial clustering of CRVO. Our cases combined to other cases reported in the literature provide arguments for the existence in some subjects of a genetic predisposition of CRVO. Additional case series are however needed to confirm this hypothesis.
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Acknowledgements
We thank the Drs Claire Monin and Christian de Gennes for providing us clinical data concerning some of the cases showed here.
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The authors have no proprietary interest in the present study
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Girmens, JF., Scheer, S., Héron, E. et al. Familial central retinal vein occlusion. Eye 22, 308–310 (2008). https://doi.org/10.1038/sj.eye.6702672
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DOI: https://doi.org/10.1038/sj.eye.6702672
