Abstract
Aim
To evaluate the efficacy of conventional argon laser for the treatment of serosanguineous maculopathy secondary to polypoidal choroidal vasculopathy (PCV).
Methods
A retrospective audit of patients who had argon laser photocoagulation to angiographically determined polypoidal lesions and subsequently followed up at 1, 3, 6, and 12 months post treatment.
Results
Twenty-one eyes (75%) had stable or improved vision at 12 months. Twenty-three eyes had extrafoveal, two eyes had juxtafoveal, and three eyes had subfoveal polyps. In the extrafoveal group, 18 eyes (78%) had stable or improved vision at 12 months. Eighteen eyes (64.3%) showed clinical or angiographic resolution of maculopathy. Three eyes (10.7%) had recurrence of polyps subfoveally, three eyes (10.7%) had subsequent choroidal neovascularisation, and four eyes (14.3%) had persistent leakage with neurosensory detachment.
Conclusion
In our study, 18 of the 23 eyes which had extrafoveal polyps had stable or improved best-corrected visual acuity and showed complete resolution of maculopathy at 12 months follow-up. Argon laser photocoagulation would appear to be most beneficial for extrafoveal PCV. However, in view of the retrospective nature of this study, the true efficacy of argon laser treatment would have to be evaluated with a larger, prospective and randomised controlled trial.
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References
Yanuzzi LA, Sorenson J, Spaide RF, Lipson B . Idiopathic polypoidal choroidal vasculopathy. Retina 1990; 10: 1–8.
Stern RM, Zakov N, Zegarra H . Multiple recurrent serous sanguineous retinal pigment epithelial detachments in black women. Am J Ophthalmol 1985; 100: 560–569.
Iijima H, Imai M, Gohodo T . Optical coherence tomography of idiopathic choroidal vasculopathy. Am J Ophthalmol 1999; 127: 301–305.
Lip PL, Hope-Ross MW, Gibson JM . Idiopathic polypoidal choroidal vasculopathy: a disease with diverse clinical spectrum and systemic associations. Eye 2000; 5: 695–700.
Lafaut BA, Aisenbrey S, van den Broecke C . Polypoidal choroidal vasculopathy pattern in age-related macular degeneration. Retina 2000; 20: 650–654.
Okubo A, Sameshima M, Uemara A . Clinicopathological correlation of polypoidal choroidal vasculopathy revealed by ultrastructural study. Br J Ophthalmol 2002; 86: 1093–1098.
Moorthy RS, Lyon AT, Rabb MF, Spaide RF, Yanuzzi LA, Jampol LM . Idiopathic polypoidal choroidal vasculopathy of the macula. Ophthalmology 1998; 105: 1380–1385.
Yannuzzi LA, Ciardella A, Spaide RF, Rabb MF, Freund KB, Orlock . The expanding clinical spectrum of idiopathic polypoidal choroidal vasculopathy. Arch Ophthalmol 1997; 115: 478–485.
Spaide RF, Yannuzzi LA, Slakter JS, Sorenson J, Orlach DA . Indocyanine green videoangiography of idiopathic choroidal vasculopathy. Retina 1995; 15: 100–110.
Uyama M, Wada M, Nagai Y . Polypoidal choroidal vasculopathy; a natural history. Am J Ophthalmol 2002; 133: 639–648.
Yuzawa M, Mori R, Haruyama M . A study of laser photocoagulation for polypoidal choroidal vasculopathy. Jpn J Ophthalmol 2003; 47 (4): 379–384.
Nishijima K, Takahashi M, Akita J, Katsuta H, Tanemura M, Aikawa H . Laser photocoagulation of indocyanine green angiographically identified feeder vessels to idiopathic polypoidal choroidal vasculopathy. Am J Ophthalmol 2004; 137 (4): 770–773.
Vedantham V, Kolluru C, Ramasamy K . Treatment of polypoidal choroidal vasculopathy with transpupillary thermotherapy; an interventional case report. Eye 2005; 19 (8): 915–917.
Chan WM, Lam DS, Lai TY, Liu DT, Li KK, Yao Y . Photodynamic therapy with verteporfin for symptomatic polypoidal choroidal vasculopathy: one year results of a prospective case series. Ophthalmology 2004; 111 (8): 1176–1184.
Quaranta M, Mauget-Faysse M, Coscas G . Exudative idiopathic polypoidal choroidal vasculopathy and photodynamic therapy with verteporfin. Am J Ophthalmol 2002; 134: 277–280.
Spaide RF, Donsoff I, Lam DL, Yanuzzi LA, Jampol LM, Slakter J . Treatment of polypoidal choroidal vasculopathy with photodynamic therapy. Retina 2002; 22: 529–535.
Shiraga F, Matsua T, Yokoe S, Takasu I, Okanouchi T, Ohtsuki H . Surgical treatment of submacular haemorrhage associated with idiopathic polypoidal choroidal vasculopathy. Am J Ophthalmol 1999; 128: 147–154.
Terasaki H, Miyake Y, Suzuki T, Nakamura M, Nagasaka T . Polypoidal choroidal vasculopathy treated with macular translocation: clinical pathological correlation. Br J Ophthalmol 2002; 86: 321–327.
Gomez-Ulla F, Gonzalez F, Torreiro MG . Diode laser photocoagulation in idiopathic polypoidal choroidal vasculopathy. Retina 1998; 18 (5): 481–483.
Vilaplana D, Castilla M, Poposki V . Laser photocoagulation in idiopathic polypoidal choroidal vasculopathy. Over one year follow up. Arch Soc Esp Oftalmol 2005; 80 (10): 597–602.
Holladay JT . Visual acuity measurements. J Cataract Refract Surg 2004; 30: 287–290.
Kwok AK, Lai TY, Chan CW, Neoh EL, Lam DS . Polypoidal choroidal vasculopathy in Chinese patients. Br J Ophthalmol 2002; 86: 892–897.
Lafaut BA, Leys AM, Snyers B, Rasquin F, De Laey JJ . Polypoidal choroidal vasculopathy in Caucasians. Graefes Arch Clin Exp Ophthalmol 2000; 238: 752–759.
Ahuja RM, Stanga PE, Vingerling JR, Reck AC, Bird AC . Polypoidal choroidal vasculopathy in exudative and haemorrhagic pigment epithelial detachments. Br J Ophthalmol 2000; 84: 479–484.
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Meeting presentation: This paper was presented at the 2005 American Academy of Ophthalmology Annual Meeting, Chicago
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Lee, MW., Yeo, I., Wong, D. et al. Argon laser photocoagulation for the treatment of polypoidal choroidal vasculopathy. Eye 23, 145–148 (2009). https://doi.org/10.1038/sj.eye.6702955
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DOI: https://doi.org/10.1038/sj.eye.6702955
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