Figure 5
From: In vivo restoration of RhoB expression leads to ovarian tumor regression
Fluorescence analysis of tumor-bearing mice by in vivo stereomicroscopy. (a) Enhanced green fluorescent protein (eGFP) expressing OVCAR-3 cells (107) were injected intraperitoneally (i.p.) into nude mice. Mice were killed 8 or 13 days post-injection and analyzed by fluorescence stereomicroscopy. (b) Ten days after the i.p. injections of 107 parental OVCAR-3 cells (ascites), mice were injected i.p. with AdeGFP (108 particles in 500 μl saline solution). Mice were killed 36 h post-injection and analyzed by fluorescence stereomicroscopy. Representative images of eGFP fluorescence in the stomach, liver, ovary and uterus are presented. (Int, intestine; Lc, uterine left cord; liv, liver; Ov, ovary; Pa, pancreas; Pl, parietal layer; Rc, uterine right cord; retro, retro peritoneum; Sp, spleen; st, sternum; sto, stomach; Ut, uterus).
