Table 1 Sequence characters of 4C2 and 2E6

From: A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein

mAbs

 

V segment

J segment

C segment

CDR1 sequence

CDR2 sequence

CDR3 sequence

4C2

H chain

IGHV5-6-4*01

IGHJ2*01

IGHG1*01

GFTFSSYT

ISSGGSYT

TRDGNDYDY

L chain

IGKV10-96*01

IGKJ1*01

IGKC*01

QDISNY

YTS

QQGNTLPRT

2E6

H chain

IGHV2-6-7*01

IGHJ2*01

IGHG1*01

GFSLTGYG

IWGDGST

ARVGDYGDYFDY

L chain

IGKV12-44*01

IGKJ1*01

IGKC*01

ENIYSY

NAK

QHHYGTPWT

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