Protein kinase N3 (PKN3; also known as PKNβ and PRK3) is a member of a subfamily of three isozymes within the AGC serine/threonine protein kinase family (
Biochem. Soc. Trans. 49, 217–235; 2021). PKN1 and PKN2 are expressed ubiquitously, while the expression of PKN3 is enriched in some cancer cell lines and there is interest in its potential as an anticancer target.
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Acknowledgements
This article is part of a series from the NIH Common Fund Illuminating the Druggable Genome (IDG) program. The goal of IDG is to catalyse research on understudied proteins from druggable gene families by providing reagents, phenotypes and a mineable database; focusing on GPCRs, kinases and ion channels. For more information, see https://druggablegenome.net/
Competing Interests
The authors declare no competing interests.
