Abstract
Purpose
To better understand the reference values and adequate discrimination values of colour vision function with described quantitative systems for the Lanthony desaturated D-15 panel (D-15DS).
Methods
A total of 1042 Japanese male officials were interviewed and underwent testing using Ishihara pseudoisochromatic plates, standard pseudoisochromatic plates part 2, and the D-15DS. The Farnsworth–Munsell (F–M) 100-hue test and the criteria of Verriest et al were used as definitive tests. Outcomes of the D-15DS were calculated using Bowman's Colour Confusion Index (CCI). The study design included two criteria. In criterion A, subjects with current or past ocular disease and a best-corrected visual acuity less than 0.7 on a decimal visual acuity chart were excluded. In criterion B, among subjects who satisfied criterion A, those who had a congenital colour sense anomaly were excluded.
Results
Overall, the 90th percentile (95th percentile) CCI values for criteria A and B in the worse eye were 1.70 (1.95) and 1.59 (1.73), respectively. In subjects satisfying criterion B, the area under the receiver operating characteristic curve was 0.951 (95% confidence interval, 0.931–0.971). The CCI discrimination values of 1.52 or 1.63 showed 90.3% sensitivity and 90% specificity, or 71.5% sensitivity and 95% specificity, respectively, for discriminating acquired colour vision impairment (ACVI).
Conclusion
We provided the 90th and 95th percentiles in a young to middle-aged healthy population. The CCI is in good agreement with the diagnosis of ACVI. Our results could be helpful for using D-15DS for screening purposes.
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Acknowledgements
The authors thank The Okubo Color Study team, in particular, K Tanaka for subject recruitment; A Katagiri for helping in preparing the study; K Sintomi, Y Usuda, T Kanazaki, N Nakai, Y Komatsu, and T Bessho for clinical input; and the volunteers for participating in the study. In addition, we thank Ms Lynda Charters for her linguistic and editorial support.
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Shoji, T., Sakurai, Y., Chihara, E. et al. Reference intervals and discrimination values of the Lanthony desaturated D-15 panel test in young to middle-aged Japanese army officials: the Okubo Color Study Report 1. Eye 23, 1329–1335 (2009). https://doi.org/10.1038/eye.2008.292
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DOI: https://doi.org/10.1038/eye.2008.292
