Abstract
Purpose
To assess the course of macular thickness change in relation to visual acuity improvement, in patients being operated for idiopathic epimacular membrane by 23-gauge pars plana vitrectomy.
Materials and methods
The clinical charts of 21 eyes of 19 consecutive patients (9 male and 10 female) were assessed retrospectively. Postoperatively, patients were followed up by best-corrected Snellen visual acuity (BCVA), a thorough ophthalmological examination, including fundoscopy, retinal thickness, and macular morphology as demonstrated by optical coherence tomography. The main outcome measures of the study were changed in central macular thickness (CMT)and visual acuity during the follow-up period.
Results
The mean duration of follow-up was 15.9±1.0 months (range 12–24 months). Mean baseline BCVA improved from 0.22±0.03 (decimal fraction) to 0.50±0.07 at the last visit (P=0.001), whereas baseline CMT (408 μm) decreased to 283 μm at final examination (P=0.001). During the follow-up, 10 eyes (47%) achieved 0.5 or better BCVA. The first significantly lower CMT readings were obtained at third-month visit while BCVA showed an improvement with the significant difference following 9 months after the surgery. In total, 8 out of 11 phakic eyes underwent cataract extraction with a mean of 6.8 months (range 1–12 months).
Conclusions
After a successful epimacular membrane removal, functional recovery takes at least 9 months in comparison to much early resolution in macular oedema that was evident at third month following the surgery.
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References
Johnson TM, Johnson MW . Epiretinal membrane. In: Yanoff M, Duker JS (eds). Ophthalmology, 3rd ed. Elsevier Inc: China, 2004, pp 686–687.
Harada C, Mitamura Y, Harada T . The role of cytokines and trophic factors in epiretinal membranes: involvement of signal transduction in glial cells. Prog Retin Eye Res 2006; 25: 149–164.
Pesin SR, Olk RJ, Grand MG, Boniuk I, Arribas NP, Thomas MA et al. Vitrectomy for premacular fibroplasia. Prognostic factors, long-term follow-up, and time course of visual improvement. Ophthalmology 1991; 98: 1109–1114.
Rice TA, De Bustros S, Michels RG, Thompson JT, Debanne SM, Rowland DY . Prognostic factors in vitrectomy for epiretinal membranes of the macula. Ophthalmology 1986; 93: 602–610.
Sakamato T, Ishibashi T . Visualizing vitreous in vitrectomy by triamcinolone. Graefes Arch Clin Exp Ophthalmol 2009; 247: 1153–1163.
Schadlu R, Tehrani S, Shah GK, Prasad AG . Long-term follow-up results of ilm peeling during vitrectomy surgery for premacular fibrosis. Retina 2008; 28: 853–857.
Machemer R . Experimental retinal detachment in the owl monkey. II. Histology of retina and pigment epithelium. Am J Ophthalmol 1968; 66: 396–410.
Machemer R . Experimental retinal detachment in the owl monkey. IV. The reattached retina. Am J Ophthalmol 1968; 66: 1075–1091.
Anderson DH, Stern WH, Fisher SK, Erickson PA, Borgula GA . Retinal detachment in the cat: the pigment epithelial–photoreceptor interface. Invest Ophthalmol Vis Sci 1983; 24: 906–926.
Stiles WS, Crawford BH . The luminous efficiency of rays entering the eye pupil at different points. Proc R Soc Lond B Biol Sci 1933; 112: 428–450.
Kanis MJ, van Norren D . Delayed recovery of the optical Stiles–Crawford effect in a case of central serous chorioretinopathy. Br J Ophthalmol 2008; 92: 292–294.
Fitzgerald CR, Birch DG, Enoch JM . Functional analysis of vision in patients after retinal detachment repair. Arch Ophthalmol 1980; 98: 1237–1244.
Tso MOM . Pathology of cystoid macular edema. Ophthalmology 1982; 89: 902–915.
Ripps H, Weale RA . Photo-labile changes and the directional sensitivity of the human fovea. J Physiol 1964; 173: 57–64.
Ferreira Saraceno JJ, Mateus IM, Lopes Machado T, Gonçalves VP, Negretto AD, Nakashima Y et al. Study on macular morphology after removal of the idiopathic epiretinal membrane using optical coherence tomography (OCT): a pilot study. Arq Bras Oftalmol 2007; 70: 935–938.
Trese MT, Chandler DB, Machemer R . Macular pucker I Prognostic criteria. Graefes Arch Klin Exp Ophthalmol 1983; 221: 12–15.
Massin P, Allouch C, Haouchine B, Metge F, Paques M, Tangui L et al. Optical coherence tomography of idiopathic macular epiretinal membranes before and after surgery. Am J Opthalmol 2000; 130: 732–739.
Thompson JT . Vitrectomy for epiretinal membranes with good visual acuity. Trans Am Ophthalmol Soc 2004; 102: 97–103.
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This paper was presented as a poster at 9th EURETINA Congress, Nice, France, 2009
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Çekiç, O., Çakır, M., Alagöz, N. et al. Retinal thickness change in relation to visual acuity improvement after 23-gauge vitrectomy for idiopathic epimacular membrane. Eye 25, 180–184 (2011). https://doi.org/10.1038/eye.2010.176
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DOI: https://doi.org/10.1038/eye.2010.176
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