Abstract
Purpose
To determine whether horizontal macular contraction caused by epiretinal membranes (ERMs) improves after surgical removal.
Methods
In this prospective, single-center, observational study, 63 consecutive patients with unilateral idiopathic ERM in one eye and no retinal disease in the fellow eye underwent pars plana vitrectomy. Fundus photography and optical coherence tomography (OCT) were performed preoperatively and at 3 months postoperatively. The area enclosed by superior and inferior major vessels from the optic disc to the fovea (area under major vessel (AUV)) and the macroscopic diverging angle (MDA) between superior and inferior major vessels were calculated using digital image analysis of fundus photographs and compared pre- and postoperatively.
Results
AUV was significantly smaller in the eyes with ERM compared with the normal fellow eyes (P<0.001). Significant postoperative change in AUV and MDA was demonstrated after ERM removal (P<0.001). However, postoperative AUV of grade 2 and 3 ERM eyes was still significantly smaller than that of normal fellow eyes. Macular thickness differences measured with stratus OCT were positively correlated with AUV differences.
Conclusions
Retinal topographic changes caused by ERM improved in part after ERM removal. The improvement of topographic changes were correlated with tomographic changes detected with OCT.
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References
McDonald HR, Verre WP, Aaberg TM . Surgical management of idiopathic epiretinal membranes. Ophthalmology 1986; 93: 978–983.
Stern WH, Fisher SK, Anderson DH, O'Donnell JJ, Erickson PA, Lewis GP et al. Epiretinal membrane formation after vitrectomy. Am J Ophthalmol 1982; 93: 757–772.
Kono T, Kohno T, Inomata H . Epiretinal membrane formation. Light and electron microscopic study in an experimental rabbit model. Arch Ophthalmol 1995; 113: 359–363.
Forte R, Pascotto F, de Crecchio G . Visualization of vitreomacular tractions with en face optical coherence tomography. Eye 2007; 21: 1391–1394.
Koizumi H, Spaide RF, Fisher YL, Freund KB, Klancnik Jr JM, Yannuzzi LA . Three-dimensional evaluation of vitreomacular traction and epiretinal membrane using spectral-domain optical coherence tomography. Am J Ophthalmol 2008; 145: 509–517.
Suzuki T, Terasaki H, Niwa T, Mori M, Kondo M, Miyake Y . Optical coherence tomography and focal macular electroretinogram in eyes with epiretinal membrane and macular pseudohole. Am J Ophthalmol 2003; 136: 62–67.
Davison JA, Chylack LT . Clinical application of the lens opacities classification system III in the performance of phacoemulsification. J Cataract Refract Surg 2003; 29: 138–145.
Kwok AK, Lai TY, Yew DT, Li WW . Internal limiting membrane staining with various concentrations of indocyanine green dye under air in macular surgeries. Am J Ophthalmol 2003; 136: 223–230.
Matsumoto C, Arimura E, Okuyama S, Takada S, Hashimoto S, Shimomura Y . Quantification of metamorphopsia in patients with epiretinal membranes. Invest Ophthalmol Vis Sci 2003; 44: 4012–4016.
Gupta P, Sadun AA, Sebag J . Multifocal retinal contraction in macular pucker analyzed by combined optical coherence tomography/scanning laser ophthalmoscopy. Retina 2008; 28: 447–452.
Grewing R, Mester U . Results of surgery for epiretinal membranes and their recurrences. Br J Ophthalmol 1996; 80: 323–326.
Rohrschneider K . Determination of the location of the fovea on the fundus. Invest Ophthalmol Vis Sci 2004; 45: 3257–3258.
Minchiotti S, Stampachiacchiere B, Micera A, Lambiase A, Ripandelli G, Billi B et al. Human idiopathic epiretinal membranes express NGF and NGF receptors. Retina 2008; 28: 628–637.
Niwa T, Terasaki H, Kondo M, Piao CH, Suzuki T, Miyake Y . Function and morphology of macula before and after removal of idiopathic epiretinal membrane. Invest Ophthalmol Vis Sci 2003; 44: 1652–1656.
Massin P, Allouch C, Haouchine B, Metge F, Paques M, Tangui L et al. Optical coherence tomography of idiopathic macular epiretinal membranes before and after surgery. Am J Ophthalmol 2000; 130: 732–739.
Wilkins JR, Puliafito CA, Hee MR, Duker JS, Reichel E, Coker JG et al. Characterization of epiretinal membranes using optical coherence tomography. Ophthalmology 1996; 103: 2142–2151.
Suh MH, Seo JM, Park KH, Yu HG . Associations between macular findings by optical coherence tomography and visual outcomes after epiretinal membrane removal. Am J Ophthalmol 2009; 147: 473–480.e3.
Asaria R, Garnham L, Gregor ZJ, Sloper JJ . A prospective study of binocular visual function before and after successful surgery to remove a unilateral epiretinal membrane. Ophthalmology 2008; 115: 1930–1937.
Villate N, Lee JE, Venkatraman A, Smiddy WE . Photoreceptor layer features in eyes with closed macular holes: optical coherence tomography findings and correlation with visual outcomes. Am J Ophthalmol 2005; 139: 280–289.
Lardenoye CW, Probst K, DeLint PJ, Rothova A . Photoreceptor function in eyes with macular edema. Invest Ophthalmol Vis Sci 2000; 41: 4048–4053.
Murakami T, Tsujikawa A, Ohta M, Miyamoto K, Kita M, Watanabe D et al. Photoreceptor status after resolved macular edema in branch retinal vein occlusion treated with tissue plasminogen activator. Am J Ophthalmol 2007; 143: 171–173.
Richter-Mueksch S, Vecsei-Marlovits PV, Sacu SG, Kiss CG, Weingessel B, Schmidt-Erfurth U . Functional macular mapping in patients with vitreomacular pathologic features before and after surgery. Am J Ophthalmol 2007; 144: 23–31.
Donati G, Kapetanios AD, Pournaras CJ . Complications of surgery for epiretinal membranes. Graefes Arch Clin Exp Ophthalmol 1998; 236: 739–746.
Wong JG, Sachdev N, Beaumont PE, Chang AA . Visual outcomes following vitrectomy and peeling of epiretinal membrane. Clin Experiment Ophthalmol 2005; 33: 373–378.
Thompson JT . Epiretinal membrane removal in eyes with good visual acuities. Retina 2005; 25: 875–882.
Acknowledgements
This study has been supported in part by grants of the Korea Healthcare technology R&D Project, Ministry for Health, Welfare & Family Affairs, Republic of Korea (A080588).
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Yang, H., Kim, S., Jung, Y. et al. Improvement of horizontal macular contraction after surgical removal of epiretinal membranes. Eye 25, 754–761 (2011). https://doi.org/10.1038/eye.2011.48
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DOI: https://doi.org/10.1038/eye.2011.48
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