Abstract
Purpose
To evaluate circumpapillary retinal nerve fiber layer (cpRNFL) and ganglion cell complex (GCC) after ocular blunt trauma.
Methods
Best-corrected visual acuity (BCVA), cpRNFL and GCC were evaluated by RTVue-100 OCT in all consecutive patients with previous monocular blunt trauma seen between January 2012 and December 2012.
Results
Twenty-two patients (11 females, 11 males, mean age 43.9±14.2 years) were included in the study. Patients were seen after a mean of 8.42±13.3 (range, 0.08–55.3) years from ocular blunt trauma. BCVA was normal in 11 cases and was less than 0.4 LogMAR in all cases. In 9/22 patients (40.9%), cpRNFL and GCC were reduced, whereas in one case an isolated reduction of GCC with normal cpRNFL was present. In patients with reduction of cpRNFL and GCC, mean BCVA was 0.17±0.17 LogMAR. In 6/9 patients (66.6%) with cpRNFL and GCC reduction, BCVA was ≤0.1 LogMAR.
Conclusion
cpRNFL and GCC reduction may be present after ocular blunt trauma and may be associated with preserved visual acuity.
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References
Medeiros FA, Moura FC, Vessani RM, Susanna R Jr . Axonal loss after traumatic optic neuropathy documented by optical coherence tomography. Am J Ophthalmol 2003; 135: 406–408.
Tan O, Chopra V, Lu AT, Schuman JS, Ishikawa H, Wollstein G et al. Detection of macular ganglion cell loss in glaucoma by Fourier-domain optical coherence tomography. Ophthalmology 2009; 116: 2305–2314 e1-2.
Kim NR, Lee ES, Seong GJ, Kim JH, An HG, Kim CY . Structure-function relationship and diagnostic value of macular ganglion cell complex measurement using Fourier-domain OCT in glaucoma. Invest Ophthalmol Vis Sci 2010; 51: 4646–4651.
Medeiros FA, Susanna R Jr . Retinal nerve fiber layer loss after traumatic optic neuropathy detected by scanning laser polarimetry. Arch Ophthalmol 2001; 119: 920–921.
Meier FM, Bernasconi P, Stürmer J, Caubergh MJ, Landau K . Axonal loss from acute optic neuropathy documented by scanning laser polarimetry. Br J Ophthalmol 2002; 86: 285–287.
Miyahara T, Kurimoto Y, Kurokawa T, Kuroda T, Yoshimura N . Alterations in retinal nerve fiber layer thickness following indirect traumatic optic neuropathy detected by nerve fiber analyzer GDx-N. Am J Ophthalmol 2003; 136: 361–364.
Kanamori A, Nakamura M, Yamada Y, Negi A . Longitudinal study of retinal nerve fiber layer thickness and ganglion cell complex in traumatic optic neuropathy. Arch Ophthalmol 2012; 130: 1067–1069.
Cunha LP, Costa-Cunha LV, Malta RF, Monteiro ML . Comparison between retinal nerve fiber layer and macular thickness measured with OCT detecting progressive axonal loss following traumatic optic neuropathy. Arq Bras Oftalmol 2009; 72: 622–625.
Vessani RM, Cunha LP, Monteiro ML . Progressive macular thinning after indirect traumatic optic neuropathy documented by optical coherence tomography. Br J Ophthalmol 2007; 91: 697–698.
Kanamori A, Nakamura M, Matsui N et al. Optical coherence tomography detects characteristic retinal nerve fiber layer thickness corresponding to band atrophy of the optic discs. Ophthalmology 2004; 111: 2278–2283.
Monteiro MLR, Leal BC, Rosa AAM et al. Optical coherence tomography analysis of axonal loss in band atrophy of the optic nerve. Br J Ophthalmol 2004; 88: 896–899.
Tatsumi Y, Kanamori A, Kusuhara A, Nakanishi Y, Kusuhara S, Nakamura M . Retinal nerve fiber layer thickness in optic tract syndrome. Jpn J Ophthalmol 2005; 49: 294–296.
Gregor Z, Ryan SJ . Blood-retinal barrier after blunt trauma to the eye. Graefes Arch Clin Exp Ophthalmol 1982; 219: 205–208.
Hart JC, Blight R . Commotio retinae. Arch Ophthalmol 1979; 97: 1738.
Saleh M, Letsch J, Bourcier T, Munsch C, Speeg-Schatz C, Gaucher D . Long-term outcomes of acute traumatic maculopathy. Retina 2011; 31: 2037–2043.
Ferreras A, Pablo LE, Garway-Heath DF, Fogagnolo P, García-Feijoo J . Mapping standard automated perimetry to the peripapillary retinal nerve fiber layer in glaucoma. Invest Ophthalmol Vis Sci 2008; 49: 3018–3025.
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The study was performed with informed consent and following all the guidelines for experimental investigations required by the Institutional Review Board or Ethics Committee of which all authors are affiliated.
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Cennamo, G., Forte, R., Reibaldi, M. et al. Evaluation of retinal nerve fiber layer and ganglion cell complex thickness after ocular blunt trauma. Eye 27, 1382–1387 (2013). https://doi.org/10.1038/eye.2013.203
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DOI: https://doi.org/10.1038/eye.2013.203
