Abstract
Purpose
Malignant melanoma of the eye is an uncommon condition that is important to recognise. We describe three cases in which ocular foreign bodies have masqueraded as ocular malignant melanoma.
Methods
Interventional case reports.
Results
Case 1 describes diathermy-induced carbon particle implantation, during plaque therapy for the treatment of uveal melanoma, mimicking recurrence with extra-scleral invasion. Case 2 shows a foreign body called ‘mullite’ mimicking conjunctival melanoma. Case 3 demonstrates a conjunctival foreign body called ‘illite’ that mimicked a limbal melanocytic lesion, clinically thought to be either melanocytoma or melanoma.
Conclusion
This report highlights the importance of careful history taking, examination, and appropriate biopsy in cases of suspected malignant melanoma, to prevent unnecessary and potentially radical treatment.
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References
Scott JA, Damato BE, Smith PA, Gurney PW . Scleral explant mimicking malignant melanoma. Eye 1994; 8: 606–608.
Austin GT . Abrasive materials. Minerals Yearbook 1987; 71–84.
Shields JA, Marr BP, Shields CL, Eagle RC Jr . Conjunctival mascaroma masquerading as melanoma. Cornea 2005; 24 (4): 496–497.
Guy JR, Rao N . Graphite foreign body of conjunctiva simulating melanoma. Cornea 1986; 4: 263–266.
Gelston CD, Mandava N, Durairaj VD . Orbital foreign body masquerading as conjunctival melanoma 60 years after injury. Clin Experiment Ophthalmol 2005; 33 (6): 661–663.
Chung HS, Feder RS, Weston BC, Bryar PJ . Suture reaction masquerading as conjunctival malignancy. Can J Ophthalmol 2006; 41 (2): 207–209.
Laquis SJ, Wilson MK, Haik BG, Fleming JC, Baber W . Conjunctival mycosis masquerading as melanoma. Am J Ophthalmol 2002; 134 (1): 117–118.
Reinecke RD, Kuwabara T . Corneal deposits secondary to topical epinephrine. Arch Ophthalmol 1963; 70: 170–172.
Acknowledgements
We are indebted to Dr Gary Burdett, Principal Scientist, Analytical Sciences, Inorganics and Fibres Section, Health and Safety Laboratory, Buxton, Derbyshire, UK for performing the EDAX analysis.
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Maudgil, A., Wagner, B., Rundle, P. et al. Ocular surface foreign bodies: novel findings mimicking ocular malignant melanoma. Eye 28, 1370–1374 (2014). https://doi.org/10.1038/eye.2014.177
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DOI: https://doi.org/10.1038/eye.2014.177
