Abstract
Purpose
To evaluate the impact of myopic keratorefractive surgery on ocular alignment.
Methods
This prospective study included 194 eyes of 97 myopic patients undergoing laser refractive surgery. All patients received a complete ophthalmic examination with particular attention to ocular alignment before and 3 months after surgery.
Results
Patients with a mean age of 26.6 years and a mean refractive error of −4.83 diopters (D) myopia were treated. Asymptomatic ocular misalignment was present preoperatively in 46 (47%) patients: a small-angle heterophoria (1–8 prism diopters, PD) in 36%; and a large-angle heterophoria (>8 PD)/heterotropia in 11%. Postoperatively, the change in angles of 10 PD or greater occurred in 3% for distance and 6% for near fixation: in 7% of the patients with orthophoria, in 3% of those with a small-angle heterophoria, and in 18% of those with a large-angle heterophoria/heterotropia. No patient developed diplopia. The preoperative magnitude of myopia or postoperative refractive status was not related to the change in ocular alignment. The higher anisometropia was associated with a decrease in deviation (P=0.041 for distance and P=0.002 for near fixation), whereas the further near point of convergence tended to be related with an increase in near deviation (P=0.055).
Conclusions
Myopic refractive surgery may cause a change in ocular alignment, especially in cases with a large-angle heterophoria/heterotropia. There is also a chance of improvement of misalignment in patients with anisometropia.
Similar content being viewed by others
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Alió JL, Muftuoglu O, Ortiz D, Artola A, Pérez-Santonja JJ, de Luna GC et al. Ten-year follow-up of photorefractive keratectomy for myopia of less than -6 diopters. Am J Ophthalmol 2008; 145: 29–36.
Minnal VR, Rosenberg JB . Refractive surgery: a treatment for and a cause of strabismus. Curr Opin Ophthalmol 2011; 22: 222–225.
Hutchinson AK, Serafino M, Nucci P . Photorefractive keratectomy for the treatment of purely refractive accommodative esotropia: 6 years' experience. Br J Ophthalmol 2010; 94: 236–240.
Kirwan C, O'Keefe M, O'Mullane GM, Sheehan C . Refractive surgery in patients with accommodative and non-accommodative strabismus: 1-year prospective follow-up. Br J Ophthalmol 2010; 94: 898–902.
Stidham DB, Borissova O, Borrissov V, Prager TC . Effect of hyperopic laser in situ keratomileusis on ocular alignment and stereopsis in patients with accommodative esotropia. Ophthalmology 2002; 109: 1148–1153.
Nemet P, Levinger S, Nemet A . Refractive surgery for refractive errors which cause strabismus. Binocul Vis Strabismus Q 2002; 17: 187–190.
Kushner BJ, Kowal L . Diplopia after refractive surgery. Arch Ophthalmol 2003; 121: 315–321.
Mandava N, Donnenfeld ED, Owens PL, Kelly SE, Haight DH . Ocular deviation following excimer laser photorefractive keratectomy. J Cataract Refract Surg 1996; 22: 504–505.
Schuler E, Silverberg M, Beade P, Moadel K . Decompensated strabismus after laser in situ keratomileusis. J Cataract Refract Surg 1999; 25: 1552–1553.
Holland D, Amm M, de Decker W . Persisting diplopia after bilateral laser in situ keratomileusis. J Cataract Refract Surg 2000; 26: 1556–1557.
Yap EY, Kowal L . Diplopia as a complication of laser in situ keratomileusis surgery. Clin Exp Ophthalmol 2001; 29: 268–271.
Godts D, Tassignon MJ, Gobin L . Binocular vision impairment after refractive surgery. J Cataract Refract Surg 2004; 30: 101–109.
Kowal L, Battu R, Kushner B . Refractive surgery and strabismus. Clin Exp Ophthalmol 2005; 33: 90–96.
Yildirim R, Oral Y, Uzun A . Exodeviation following monocular myopic regression after laser in situ keratomileusis. J Cataract Refract Surg 2003; 29: 1031–1033.
Snir M, Kremer I, Weinberger D, Sherf I, Axer-Siegel R . Decompensation of exodeviation after corneal refractive surgery for moderate to high myopia. Ophthalmic Surg Lasers Imaging 2003; 34: 363–370.
Ekdawi NS, Nusz KJ, Diehl NN, Mohney BG . The development of myopia among children with intermittent exotropia. Am J Ophthalmol 2010; 149: 503–507.
Yekta A, Fotouhi A, Hashemi H, Dehghani C, Ostadimoghaddam H, Heravian J et al. The prevalence of anisometropia, amblyopia and strabismus in schoolchildren of Shiraz, Iran. Strabismus 2010; 18: 104–110.
Godts D, Trau R, Tassignon MJ . Effect of refractive surgery on binocular vision and ocular alignment in patients with manifest or intermittent strabismus. Br J Ophthalmol 2006; 90: 1410–1413.
Rajavi Z, Nassiri N, Azizzadeh M, Ramezani A, Yaseri M . Orthoptic Changes following Photorefractive Keratectomy. J Ophthalmic Vis Res 2011; 6: 92–100.
Holmes JM, Leske DA, Hatt SR, Brodsky MC, Mohney BG . Stability of near stereoacuity in childhood intermittent exotropia. J AAPOS 2011; 15: 462–467.
Holmes JM, Leske DA, Hohberger GG . Defining real change in prism-cover test measurements. Am J Ophthalmol 2008; 145: 381–385.
Scattergood KD, Brown MH, Guyton DL . Artifacts introduced by spectacle lenses in the measurement of strabismus deviations. Am J Ophthalmol 1983; 96: 439–448.
Remole A . Determining exact prismatic deviations in spectacle corrections. Optom Vis Sci 1999; 76: 783–795.
Caltrider N, Jampolsky A . Overcorrecting minus lens therapy for treatment of intermittent exotropia. Ophthalmology 1983; 90: 1160–1165.
Jampolsky A, Flom BC, Weymouth FS, Moster LE . Unequal corrected visual acuity as related to anisometropia. Arch Ophthalmol 1955; 54: 893–905.
Abbott ML, Schmid KL, Strang NC . Differences in the accommodation stimulus response curves of adult myopes and emmetropes. Ophthalmic Physiol Opt 1998; 18: 13–20.
Hashemi H, Samet B, Mirzajani A, Khabazkhoob M, Rezvan B, Jafarzadehpur E . Near Point of Accommodation and Convergence after Photorefractive Keratectomy (PRK) for Myopia. Binocul Vis Strabolog Q Simms Romano 2013; 28: 29–35.
Alió JL, Muftuoglu O, Ortiz D, Pérez-Santonja JJ, Artola A, Ayala MJ et al. Ten-year follow-up of laser in situ keratomileusis for myopia of up to −10 diopters. Am J Ophthalmol 2008; 145: 46–54.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no conflict of interest.
Additional information
Author contributions
Study concept and design (SAC); data collection (SAC, WKK, HY, and JKK); analysis and interpretation of the data (SAC, JWM); drafting of the manuscript (SAC, JWM, and SBL); critical revision of the manuscript (SAC, WKK, HY, JKK, SBL, and JBL); statistical expertise (SAC); supervision (JBL).
Rights and permissions
About this article
Cite this article
Chung, S., Kim, W., Moon, J. et al. Impact of laser refractive surgery on ocular alignment in myopic patients. Eye 28, 1321–1327 (2014). https://doi.org/10.1038/eye.2014.209
Received:
Accepted:
Published:
Issue date:
DOI: https://doi.org/10.1038/eye.2014.209