Table 2 Descriptive statistics for IOP by visit and time point

	BBFC+PGA				Vehicle+PGA
	Mean±SE IOP, mm Hg				Mean±SE IOP, mm Hg
	n	IOP	IOP change from baseline	Percent IOP change from baseline	n	IOP	IOP change from baseline	Percent IOP change from baseline
Baseline
0800 hours	88	24.5±0.3	—	—	94	24.3±0.3	—	—
1000 hours	88	22.9±0.2	—	—	94	22.6±0.3	—	—
1500 hours	88	21.7±0.3	—	—	94	21.3±0.3	—	—
1700 hours	88	21.6±0.3	—	—	94	21.2±0.4	—	—
Mean diurnal	88	22.7±0.2	—	—	94	22.4±0.3	—	—
Week 2
0800 hours	88	18.8±0.4	−5.6±0.4	−22.8±1.6	94	21.8±0.4	−2.5±0.3	−10.3±1.3
1000 hours	86	15.7±0.4	−7.2±0.4	−31.5±1.6	93	20.2±0.4	−2.4±0.3	−10.5±1.3
1500 hours	86	16.9±0.3	−4.8±0.3	−21.8±1.4	93	19.9±0.4	−1.5±0.4	−6.1±1.6
1700 hours	86	15.3±0.4	−6.3±0.4	−28.8±1.5	92	19.4±0.4	−1.8±0.3	−7.5±1.7
Mean diurnal	88	16.8±0.3	−6.0±0.3	−26.0±1.3	94	20.4±0.4	−2.0±0.3	−8.5±1.2
Week 6
0800 hours	83	19.4±0.4	−5.1±0.4	−20.6±1.5	92	21.4±0.5	−2.9±0.4	−12.0±1.4
1000 hours	83	15.8±0.4	−7.1±0.4	−30.9±1.7	92	20.2±0.4	−2.4±0.3	−10.6±1.5
1500 hours	83	17.2±0.3	−4.5±0.3	−20.6±1.4	92	19.9±0.4	−1.4±0.4	−6.1±1.6
1700 hours	83	15.6±0.3	−5.9±0.3	−27.4±1.4	92	19.9±0.5	−1.2±0.4	−5.3±1.6
Mean diurnal	83	17.0±0.3	−5.7±0.3	−24.9±1.2	92	20.4±0.4	−2.0±0.3	−8.5±1.3

Abbreviations: BBFC, fixed-combination brinzolamide 1%/brimonidine 0.2%; IOP, intraocular pressure; PGA, prostaglandin analog; SE, standard error.

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