Abstract
Purpose
Management of refractive errors after cataract surgery includes spectacles or contact lens, secondary laser vision correction, intraocular lens (IOL) exchange, or piggyback lens implantation. We evaluated for the first time a single-piece hydrophilic acrylic IOL designed for supplementary sulcus fixation in postmortem pseudophakic human eyes.
Methods
Pseudophakic human cadaver eyes were imaged by anterior segment optical coherence tomography (AS-OCT) to assess position of the primary IOL. Eyes were prepared as per the Miyake-Apple technique. The supplementary IOL (Medicontur A4 Addon IOL family) was then inserted into the ciliary sulcus. AS-OCT and photographs from anterior and posterior views were used to assess IOL centration, tilt, and interlenticular distance from the primary IOL.
Results
Data were obtained from 12 eyes having primary IOLs of varying materials and designs in the bag and representing different sizes of eyes and severity of Soemmering’s ring formation. The A4 Addon IOL was successfully inserted into the ciliary sulcus and was well centered in all cases. Four cases of tilt were observed on AS-OCT: three with mild tilt due to pre-existing zonular dehiscence, and one due to a localized area of Soemmering’s ring formation. Interlenticular distance ranged from 0.34 to 1.24 mm and was not dependent on severity of Soemmering’s ring or type of primary IOL.
Conclusions
The A4 Addon IOL was designed for sulcus fixation as a supplementary lens, with a large diameter, a square-shaped optic, four smooth loop haptics, and a convex–concave optical surface. It exhibited appropriate centration and interlenticular distance with different primary in-the-bag IOLs.
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References
Mamalis N, Brubaker J, Davis D, Espandar L, Werner L . Complications of foldable intraocular lenses requiring explantation or secondary intervention—2007 survey update. J Cataract Refract Surg 2008; 34 (9): 1584–1591.
Behndig A, Montan P, Stenevi U, Kugelberg M, Zetterström C, Lundström M . Aiming for emmetropia after cataract surgery: Swedish National Cataract Register study. J Cataract Refract Surg 2012; 38 (7): 1181–1186.
Alio JL, Abdelghany AA, Fernández-Buenaga R . Management of residual refractive error after cataract surgery. Curr Opin Ophthalmol 2014; 25 (4): 291–297.
Gayton JL, Apple DJ, Peng Q, Visessook N, Sanders V, Werner L et al. Interlenticular opacification: clinicopathological correlation of a complication of posterior chamber piggyback intraocular lenses. J Cataract Refract Surg 2000; 26 (3): 330–336.
Werner L, Apple DJ, Pandey SK, Solomon KD, Snyder ME, Brint SF et al. Analysis of elements of interlenticular opacification. Am J Ophthalmol 2002; 133 (3): 320–326.
Micheli T, Cheung LM, Sharma S, Assaad NN, Guzowski M, Francis IC et al. Acute haptic-induced pigmentary glaucoma with an AcrySof intraocular lens. J Cataract Refract Surg 2002; 28 (10): 1869–1872.
Chang WH, Werner L, Fry LL, Johnson JT, Kamae K, Mamalis N . Pigmentary dispersion syndrome with a secondary piggyback 3-piece hydrophobic acrylic lens. Case report with clinicopathological correlation. J Cataract Refract Surg 2007; 33 (6): 1106–1109.
Iwase T, Tanaka N . Elevated intraocular pressure in secondary piggyback intraocular lens implantation. J Cataract Refract Surg 2005; 31 (9): 1821–1823.
Falzon K, Stewart OG . Correction of undesirable pseudophakic refractive error with the Sulcoflex intraocular lens. J Refract Surg 2012; 28 (9): 614–619.
Basarir B, Kaya V, Altan C, Karakus S, Pinarci EY, Demirok A . The use of a supplemental sulcus fixated IOL (HumanOptics Add-On IOL) to correct pseudophakic refractive errors. Eur J Ophthalmol 2012; 22 (6): 898–903.
Pereira FaS, Werner L, Milverton EJ, Coroneo MT . Miyake-Apple posterior video analysis/photographic technique. J Cataract Refract Surg 2009; 35 (3): 577–587.
Clare G, Bloom P . Bilateral ciliary sulcus implantation of secondary piggyback multifocal intraocular lenses. J Cataract Refract Surg 2007; 33 (2): 320–322.
Alfonso JF, Fernández-Vega L, Baamonde MB . Secondary diffractive bifocal piggyback intraocular lens implantation. J Cataract Refract Surg 2006; 32 (11): 1938–1943.
Meyer JJ, McGhee CN . Supplementary, sulcus-fixated intraocular lens in the treatment of spherical and astigmatic refractive errors in pseudophakic eyes after keratoplasty. Cornea 2015; 34 (9): 1052–1056.
Žiak P, Šesták M, Mojžiš P, Piñero DP . Piggyback with toric intraocular lens after corneal melting in autoimmune necrotizing vasculitis. Can J Ophthalmol 2013; 48 (3): e48–e50.
Huerva V . Piggyback multifocal IOLs for a hyperopic-presbyopic surprise after cataract surgery in high myopic patients. Cont Lens Anterior Eye 2014; 37 (1): 57–59.
Xu Y, Yang Y . Dry eye after small incision lenticule extraction and LASIK for myopia. J Refract Surg 2014; 30 (3): 186–190.
Vestergaard AH, Grauslund J, Ivarsen AR, Hjortdal JO . Efficacy, safety, predictability, contrast sensitivity, and aberrations after femtosecond laser lenticule extraction. J Cataract Refract Surg 2014; 40 (3): 403–411.
Dagres E, Khan Ma, Kyle GM, Clark D . Perioperative complications of intraocular lens exchange in patients with opacified Aqua-Sense lenses. J Cataract Refract Surg 2004; 30 (12): 2569–2573.
Lee SJ, Sun HJ, Choi KS, Park SH . Intraocular lens exchange with removal of the optic only. J Cataract Refract Surg 2009; 35 (3): 514–518.
Altaie R, Loane E, O’Sullivan K, Beatty S . Surgical and visual outcomes following exchange of opacified Hydroview intraocular lenses. Br J Ophthalmol 2007; 91 (3): 299–302.
El Awady HE, Ghanem AA . Secondary piggyback implantation versus IOL exchange for symptomatic pseudophakic residual ametropia. Graefes Arch Clin Exp Ophthalmol 2013; 251 (7): 1861–1866.
McIntyre JS, Werner L, Fuller SR, Kavoussi SC, Hill M, Mamalis N . Assessment of a single-piece hydrophilic acrylic IOL for piggyback sulcus fixation in pseudophakic cadaver eyes. J Cataract Refract Surg 2012; 38 (1): 155–162.
Acknowledgements
Michael Anderson, COA, Moran Eye Center assisted with the AS-OCT examination. Supported in part by an unrestricted grant from Research to Prevent Blindness, Inc, New York, NY, USA to the Department of Ophthalmology and Visual Sciences, University of Utah, and by a research grant from Medicontur Medical Engineering Ltd., Hungary.
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LW reports research grants from Medicontur, during the conduct of the study; grants from Abbott Medical Optics, grants from AcuFocus, grants from Alcon, grants from Anew Optics, grants from Bausch and Lomb, grants from ClarVista, grants from Hoya, grants and personal fees from PowerVision, grants from Genisphere, grants from LensGen, grants from Mynosys, grants from Omega, grants from Sharklet, outside the submitted work. NM reports research grants from Medicontur, during the conduct of the study; grants from Abbott Medical Optics, grants from Alcon Laboratories, grants from Allergan, grants and other from Anew Optics, grants from Bausch and Lomb, grants from Calhoun Vision Inc, grants from Hoya, grants from Genisphere, grants from Sharklet, grants from ClarVista, grants from LensGen, grants from Omega, grants from Mynosys, grants from PowerVision, outside the submitted work. The remaining authors declare no conflict of interest.
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Reiter, N., Werner, L., Guan, J. et al. Assessment of a new hydrophilic acrylic supplementary IOL for sulcus fixation in pseudophakic cadaver eyes. Eye 31, 802–809 (2017). https://doi.org/10.1038/eye.2016.310
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DOI: https://doi.org/10.1038/eye.2016.310
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