Abstract
Purpose
To evaluate the relationship between central corneal thickness (CCT) and horizontal corneal diameter (HCD) in eyes with uveal coloboma and microcornea.
Patients and methods
All adult patients with uveal coloboma having microcornea in at least one eye and seen between May 2014 and July 2016 at the cataract clinic of our tertiary eye care center were evaluated. The study group comprised 26 colobomatous eyes of 15 patients who had associated microcornea. The control group comprised eyes with uveal coloboma and normal-sized cornea (n=12 eyes of 9 patients). The main outcome measure included the relationship between CCT and HCD in eyes with uveal coloboma and microcornea.
Results
The mean HCD of the study and control groups was 6.97±1.28 and 11.39±0.67 mm, respectively. The mean central pachymetry of the study group was 668.4±40.2 μm compared with 555.3±41.8 μm in the control group. In both the groups, CCT was negatively correlated with HCD (R=−0.62 in the study group and R=−0.72 in the control group).
Conclusions
Uveal colobomatous eyes with microcornea have thicker corneas compared with uveal colobomatous eyes with normal diameter corneas that have normal central corneal thickness. In all the eyes with uveal coloboma, there is a negative correlation between horizontal corneal diameter and central corneal thickness.
Similar content being viewed by others
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Warburg M . Classification of microphthalmos and coloboma. J Med Genet 1993; 30: 664–669.
Mohamed A, Chaurasia S, Ramappa M, Sangwan VS, Jalali S . Lenticular changes in congenital iridolenticular choroidal coloboma. Am J Ophthalmol 2014; 158: 827–830 e2.
Tang J, Gokhale PA, Brooks SE, Blain D, Brooks BP . Increased corneal thickness in patients with ocular coloboma. J AAPOS 2006; 10: 175–177.
Filous A, Osmera J, Hlozanek M, Mahelkova G . Central corneal thickness in microphthalmic eyes with or without history of congenital cataract surgery. Eur J Ophthalmol 2011; 21: 374–378.
Bayoumi NH, El Shakankiri NM . Central corneal thickness in aphakic children with microcornea-microphthalmia. J Glaucoma 2016; 25: 497–500.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no conflict of interest.
Rights and permissions
About this article
Cite this article
Mohamed, A., Chaurasia, S., Ramappa, M. et al. Corneal thickness in uveal coloboma with microcornea. Eye 32, 586–589 (2018). https://doi.org/10.1038/eye.2017.258
Received:
Accepted:
Published:
Version of record:
Issue date:
DOI: https://doi.org/10.1038/eye.2017.258
