Abstract
Purpose
To describe the neuro-ophthalmologic findings of cholangiocarcinoma.
Methods
We report a retrospective chart review of cholangiocarcinoma patients presenting at two tertiary care centers in the Texas Medical Center.
Results
Five patients with neuro-ophthalmologic symptoms related to cholangiocarcinoma were identified. One patient presented with diplopia due to metastasis to the left medial rectus muscle, two patients had metastasis to the occipital lobe resulting in homonymous hemianopsia, one patient had involvement of the clivus resulting in sixth nerve palsy, and one presented with a hypercoagulable state-related stroke causing a homonymous hemianopsia and visual hallucinations.
Conclusions
Neuro-ophthalmic manifestations of cholangiocarcinoma depend upon both mechanism and localization. We report five cases of cholangiocarcinoma with neuro-ophthalmologic findings. To our knowledge, this is the largest such series reported in the English language ophthalmic literature.
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Poster presentation at the 2016 North American Neuro-Ophthalmology Society Annual Meeting in Tucson, AZ, USA.
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Rico, G., Smith, S., Siddiqui, Y. et al. Neuro-ophthalmologic manifestations of cholangiocarcinoma: a case series. Eye 31, 1245–1248 (2017). https://doi.org/10.1038/eye.2017.77
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DOI: https://doi.org/10.1038/eye.2017.77
