Abstract
Purpose
To quantify the additional information provided by ultra-widefield fluorescein angiography, compared with 7-field standard imaging, in patients with retinal vasculitis (RV).
Patients and methods
Retrospective case series of 106 patients.
Results
Retinal vascular pathology was identified by UWF FFA, but not by standard ETDRS 7-field area, in 62 patients (58.5%) and in 79 eyes (43.4%). The pathology included active RV (47 eyes, 25.8% of eyes); retinal ischaemia, or infarction (53 eyes, 29.1%); and retinal neovascularization (7 eyes, 3.8%). A change to management was made in 36 patients (34%). Of these, 21 (20% of all patients undergoing angiography) were made after the identification of retinal vascular pathology, which was found only on UWF FFA, outside the ETDRS area.
Conclusion
Ultra-widefield fluorescein angiography has clear advantages over standard multi-field imaging. It is currently the standard method of assessment for RV in this centre.
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Acknowledgements
This research was partially facilitated by the NIHR/Wellcome Trust Manchester CRF and the Greater Manchester Comprehensive Local Research Network by providing imaging equipment, clinical facilities, and clerical assistance.
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PES: Optos Plc. (consultancy, equipment, research funding, lecture fees, and travel expenses). The remaining authors declare no conflict of interest.
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Jones, N., Sala-Puigdollers, A. & Stanga, P. Ultra-widefield fundus fluorescein angiography in the diagnosis and management of retinal vasculitis. Eye 31, 1546–1549 (2017). https://doi.org/10.1038/eye.2017.93
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DOI: https://doi.org/10.1038/eye.2017.93
