Figure 2
From: Molecular characterisation of KIR2DS2*005, a fusion gene associated with a shortened KIR haplotype
Intron 6 sequence supports KIR2DS2*005 being a fusion gene of KIR2DS2 and KIR2DS3. The DNA sequence of KIR2DS2*005 intron 6 is compared with those of KIR2DS2*0010102 and KIR2DS3*0010301 (both from GenBank/EMBL/DDBJ accession no. AY320039). Partial sequences of exons 6 and 7 are shown underlined in capital letters. Numbering refers to the first nucleotide shown in the alignment. Dots represent identity to KIR2DS2*005, and dashes, indels. To reduce figure size, the sequence between nucleotides 800 and 2800 of KIR2DS2*005 has been omitted; in the omitted region, KIR2DS2*005 is identical to KIR2DS2*0010102, and differs from KIR2DS3*0010301 by 22 base substitutions and deletion of one nucleotide. The regions of high homology between KIR2DS2*005 and either KIR2DS2*0010102 or KIR2DS3*0010301 are shaded in the latter two sequences.
