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References
Miller, M. B. & Gilligan, P. H. Laboratory aspects of management of chronic pulmonary infections in patients with cystic fibrosis. J. Clin. Microbiol. 41, 4009–4015 (2003).
Nation, R. L. & Li, J. Colistin in the 21st century. Curr. Opin. Infect. Dis. 22, 535–543 (2009).
Craig, W. A. & Gudmundsson, S. in Antibiotics in laboratory medicine. Postantibiotic effect. (ed Lorian, V.) 296–329 Lippincott Williams and Wilkins Co., Baltimore, 1996.
Craig, W. A. Pharmacokinetic/pharmacodynamic parameters: the rational for antibacterial dosing in mice and men. Clin. Infect. Dis. 26, 1–10 (1998).
Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing, Eighteenth Informational Supplement, CLSI document M100-S18, CLSI, Wayne, Pennsylvania, USA, 2008.
Clinical and Laboratory Standards Institute. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Seventh Approved Standard, CLSI document M7-A7, CLSI, Wayne, Pennsylvania, USA, 2006.
Pillai, S. K., Moellering, R. C. Jr. & Eliopoulos, G. M. in Antibiotics in laboratory medicine. Antimicrobial Combinations (ed Lorian, V.) 365–440 Lippincott Williams and Wilkins Co., Philadelphia, 2005.
Odds, F. C. Synergy, antagonism, and what the chequerboard puts between them. J. Antimicrob. Chemother. 52, 1 (2003).
Gunderson, B. W., Ross, G. H., Ibrahim, K. H. & Rotschafer, J. C. What do we really know about antibiotic pharmacodynamics? Pharmacotherapy 21 (suppl 11), 302–318 (2001).
Howard, M., Frizell, R. & Bedwell, D. Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations. Nat. Med. 2, 467–469 (1996).
Du, M. et al. Clinical doses of amikacin provide more effective suppression of the human CFTR-G542X stop mutation than gentamicin in a transgenic CF mouse model. J. Mol. Med. 84, 573–582 (2006).
Li, J., Turnidge, J., Milne, R., Nation, R. L. & Coulthard, K. In vitro pharmacodynamic properties of colistin and colistin methanesulfonate against Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Antimicrob. Agents Chemother. 45, 781–785 (2001).
Gunderson, B. W. et al. Synergistic activity of colistin and ceftazidime against multiantibiotic-resistant Pseudomonas aeruginosa in an in vitro pharmacodynamic model. Antimicrob. Agents Chemother. 47, 905–909 (2003).
Lu, Q. et al. Nebulized and intravenous colistin in experimental pneumonia caused by Pseudomonas aeruginosa. Intensive Care Med. 36, 1147–1155 (2010).
Michalopoulos, A. et al. Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis. Crit. Care. 9, R53–R59 (2005).
Ratjen, F. et al. Pharmacokinetics of inhaled colistin in patients with cystic fibrosis. J. Antimicrob. Chemother. 57, 306–311 (2006).
Giamarellou, H. & Poulakou, G. Multidrug-resistant gram-negative infections: what are the treatment options? Drugs 69, 1879–1901 (2009).
Santré, C. et al. Amikacin levels in bronchial secretions of 10 pneumonia patients with respiratory support treated once daily versus twice daily. Antimicrob. Agents Chemother. 39, 264–267 (1995).
Goldstein, I. et al. Lung tissue concentrations of nebulized amikacin during mechanical ventilation in piglets with healthy lungs. Am. J. Respir. Crit. Care Med. 165, 171–175 (2002).
Döring, G. et al. Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus. Eur. Respir. J. 16, 749–767 (2000).
Giamarellos-Bourboulis, E. J., Xirouchaki, E. & Giamarellou, H. Interactions of colistin and rifampin on multidrug-resistant Acinetobacter baumannii. Diagn. Microbiol. Infect. Dis. 40, 117–120 (2001).
Giamarellos-Bourboulis, E. J., Karnesis, L. & Giamarellou, H. Synergy of colistin with rifampin and trimethoprim/sulfamethoxazole on multidrug-resistant Stenotrophomonas maltophilia. Diagn. Microbiol. Infect. Dis. 44, 259–263 (2002).
Giamarellos-Bourboulis, E. J., Sambatakou, H., Galani, I. & Giamarellou, H. In vitro interaction of colistin and rifampin on multidrug-resistant Pseudomonas aeruginosa. J. Chemother. 15, 235–238 (2003).
Tascini, C., Ferranti, S., Messina, F. & Menichetti, F. In vitro and in vivo synergistic activity of colistin, rifampin, and amikacin against a multiresistant Pseudomonas aeruginosa isolate. Clin. Microbiol. Infect. 6, 690–691 (2000).
Güzel, C. B. & Gerçeker, A. A. In vitro activities of various antibiotics, alone and in combination with colistin methanesulfonate, against Pseudomonas aeruginosa strains isolated from cystic fibrosis patients. Chemotherapy 54, 147–151 (2008).
Gerceker, A. A. & Otuk, G. Postantibiotic effect of imipenem, alone and in combination with amikacin, on Pseudomonas aeruginosa. Chemotherapy 41, 433–436 (1995).
Li, R. C. & Tang, M. C. Post-antibiotic effect induced by an antibiotic combination: influence of altered susceptibility to individual components. J. Antimicrob. Chemother. 55, 583–586 (2005).
Buxbaum, A. & Georgopoulos, A. Postantibiotic effect of ceftriaxone and gentamicin alone and in combination on Klebsiella pneumoniae, Pseudomonas aeruginosa and Streptococcus viridans. Infection 24, 459–464 (1996).
Giamarellos-Bourboulis, E. J. et al. Postantibiotic effect of antimicrobial combinations on multidrug-resistant Pseudomonas aeruginosa. Diagn. Microbiol. Infec. Dis. 51, 113–117 (2005).
Acknowledgements
This work was supported by a grant from the Research Fund of The University of Istanbul. Project number: T–816/27122005. We thank Zayre Erturan, for supplying the P. aeruginosa isolates.
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Bozkurt-Güzel, Ç., Gerçeker, A. Post-antibiotic effect of colistin, alone and in combination with amikacin, on Pseudomonas aeruginosa strains isolated from cystic fibrosis patients. J Antibiot 65, 83–86 (2012). https://doi.org/10.1038/ja.2011.101
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DOI: https://doi.org/10.1038/ja.2011.101