Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Cengiz, M. et al. Molecular characterization of quinolone resistance in Escherichia coli from animals in Turkey. Vet. Rec. 171, 155 (2012).
Hopkins, K. L., Davies, R. H. & Threlfall, E. J. Mechanisms of quinolone resistance in Escherichia coli and Salmonella: recent developments. Int. J. Antimicrob. Ag 25, 358–373 (2005).
Poirel, L. et al. Expanded-spectrum β-lactamase and plasmid-mediated quinolone resistance. Emerg. Infect. Dis. 13, 803–805 (2007).
Rodriguez-Martinez, J. M., Briales, A., Velasco, C., Martinez-Martinez, L. & Pascual, A. Discrepancies in fluoroquinolone clinical categoris between the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and CLSI for Escherichia coli harbouring qnr genes and mutations in gyrA and parC. J. Antimicrob. Chemoth. 66, 1406–1453 (2011).
Blondeau, J. M., Borsos, S., Blondeau, L. D. & Blondeau, B. J. In vitro killing of Escherichia coli, Staphylococcus pseudintermedius and Pseudomonas aeruginosa by enrofloxacin in combination with its active metabolite ciprofloxacin using clinically relevant drug concentrations in the dog and cat. Vet. Microbiol 155, 284–290 (2012).
Coulet, M., Van Borssum Waalkes, M., Cox, P. & Lohuis, J. In vitro and in vivo pharmacodynamic properties of the fluoroquinolone Ibafloxacin. J. Vet. Pharmacol. Therap. 25, 401–411 (2002).
Lautzenhiser, S. J., Fialkowski, J. P., Bjorling, D. & Rosin, E. In vitro antibacterial activity of enrofloxacin and ciprofloxacin in combination against Escherichia coli and staphylococcal clinical isolates from dogs. Res. Vet. Sci. 70, 239–241 (2001).
Pankey, G. A. & Ashcraft, D. S. In vitro synergy of ciprofloxacin and gatifloxacin against ciprofloxacin-resistant Pseudomonas aeruginosa. Antimicrob. Agents Ch. 49, 2959 (2005).
Clinical Laboratory Standards Institute.. Performance Standards for Antimicrobial Susceptibility Testing; Nineteenth Informational Supplement M100-S19, C. S.: Wayne, PA, USA, (2009).
Everett, M. J., Jin, Y. F., Ricci, V. & Piddock, L. J. V. Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals. Antimicrob. Agents Ch. 40, 2380–2386 (1996).
Wang, M. et al. New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. Antimicrob. Agents Ch. 53, 1892–1897 (2009).
Robicsek, A., Strahilevitz, J., Sahm, D. F., Jocoby, G. A. & Hooper., D. C. qnr prevalence in ceftazidime-resistant Enterobacteriaceae isolates from United States. Antimicrob. Agents Ch. 50, 2872–2874 (2006).
Elipoulos, G. M. & Moellering, R. C. Antimicrobial combinations in Antibiotic in Laboratory Medicine 4th edn, ed.Lorian V, 330–396 William and Wilkins: Baltimore, MD, (1996).
Petersen, P. J., Labthavikul, P., Jones, H. C. & Bradford, P. A. In vitro antibacterial avtivities of tigecycline in combination with other antimicrobial agents determined by chequerboard and time-kill kinetic analysis. J. Antimicrob. Chemoth. 57, 573–576 (2006).
Prescott, J. F., Baggot, J. D. & Walker, R. D. Antimicrobial Theraphy in Veterinary Medicine 3rd edn. Iowa State University Press: Ames, 320–321 (2000).
Livermore, D. M. Has the era of untreatable infections arrived? J. Antimicrob. Chemoth. 64 (Suppl. 1), 29–36 (2009).
Karczmarczyk, M., Martins, M., Quinn, T., Leonard, N. & Fanning, S. Mechanisms of fluoroquinolone resistance in Escherichia coli isolates from food-producing animals. Appl Environ Microbiol. 77, 7113–7120 (2011).
Cengiz, M. et al. In vitro bactericidal activity of enrofloxacin against gyrA mutant and qnr-containing Escherichia coli isolates from animals. Vet. Rec. 172, 474 (2013).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Cengiz, M., Sahinturk, P. Assessment of synergistic interactions of danofloxacin and orbifloxacin against quinolone-resistant Escherichia coli isolated from animals by the checkerboard and time-kill methods. J Antibiot 66, 629–631 (2013). https://doi.org/10.1038/ja.2013.62
Received:
Revised:
Accepted:
Published:
Issue date:
DOI: https://doi.org/10.1038/ja.2013.62