Abstract
In epidemiological studies, it is easier to glean information from isolated populations with simple genetic backgrounds than from populations with relatively complex genetic backgrounds. Regarded as an isolated population, the Minz (Hei-Yi Zhuang) in Napo County (in the China–Vietnam borderland) has been the subject of numerous recent studies. To assess the genetic isolation of this population, we studied Y chromosome and mitochondrial DNA from Minz and Han in Napo. Both populations exhibited southern Chinese genetic characteristics in both paternal and maternal lineages. Using NETWORK analyses, we found pronounced gene flow between these two populations only in maternal lineages. We also observed gene flow from other populations into the Minz gene pool. We thus concluded that the Minz is not a genetically isolated population and it is increasingly difficult to find isolated populations in mainland East Asia.
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Acknowledgements
We especially thank all of those who donated samples. Our research was supported by the Natural Science Foundation of Shanghai (10ZR1402200) to HL; the National Natural Science Foundation of China (39993420) and Guangxi Natural Science Foundation (GSN0728160, GSY0542044) to SLP; the National Outstanding Youth Science Foundation of China (30625016), National Science Foundation of China (30890034), 863 Program (2007AA02Z312) and Shanghai Leading Academic Discipline Project (B111) to LJ; and National Science Foundation of China (30360038) to RY.
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Zhao, Q., Pan, S., Qin, Z. et al. Gene flow between Zhuang and Han populations in the China–Vietnam borderland. J Hum Genet 55, 774–776 (2010). https://doi.org/10.1038/jhg.2010.107
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DOI: https://doi.org/10.1038/jhg.2010.107
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