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Holland, P. W., Booth, H. A. & Bruford, E. A. Classification and nomenclature of all human homeobox genes. BMC Biol. 5, 47 (2007).
Merabet, S. & Mann, R. S. To be specific or not: the critical relationship between Hox and TALE proteins. Trends Genet. 6, 334–347 (2016).
Nakamura, T., Jenkins, N. A. & Copeland, N. G. Identification of a new family of Pbx-related homeobox genes. Oncogene 13, 2235–2242 (1996).
Geerts, D., Schilderink, N., Jorritsma, G. & Versteeg, R. The role of the MEIS homeobox genes in neuroblastoma. Cancer Lett. 197, 87–92 (2003).
Johansson, S., Berland, S., Gradek, G. A., Bongers, E., de Leeuw, N ., Pfundt, R et al. Haploinsufficiency of MEIS2 is associated with orofacial clefting and learning disability. Am. J. Med. Genet. A 164 A, 1622–1626 (2014).
Larsen, K. B., Lutterodt, M. C., Laursen, H., Graem, N., Pakkenberg, B., Møllgård, K. et al. Spatiotemporal distribution of PAX6 and MEIS2 expression and total cell numbers in the ganglionic eminence in the early developing human forebrain. Dev. Neurosci. 32, 149–162 (2010).
Machon, O., Masek, J., Machonova, O., Krauss, S. & Kozmik, Z. Meis2 is essential for cranial and cardiac neural crest development. BMC Dev. Biol. 6, 40 (2015).
Crowley, M. A., Conlin, L. K., Zackai, E. H., Deardorff, M. A., Thiel, B. D. & Spinner, N. B. Further evidence for the possible role of MEIS2 in the development of cleft palate and cardiac septum. Am. J. Med. Genet. A 152 A, 1326–1327 (2010).
Louw, J. J., Corveleyn, A., Jia, Y., Hens, G., Gewillig, M. & Devriendt, K. MEIS2 involvement in cardiac development, cleft palate, and intellectual disability. Am. J. Med. Genet. A 167 A, 1142–1146 (2015).
Fujita., A., Isidor, B., Piloquet, H., Corre, P., Okamoto, N., Nakashima, M et al. De novo MEIS2 mutation causes syndromic developmental delay with persistent gastro-esophageal reflux. J. Hum. Genet 61, 835–838 (2016).
Thompson, H., Blentic, A., Watson, S., Begbie, J. & Graham, A. The formation of the superior and jugular ganglia: insights into the generation of sensory neurons by the neural crest. Dev. Dyn. 239, 439–445 (2010).
Browning, K.N. Role of central vagal 5-HT3 receptors in gastrointestinal physiology and pathophysiology. Front Neurosci. 9, 413 (2015).
Gilbert, S. F Developmental Biology, 10th edn (Sinauer Associates, Inc, Sunderland, MA, USA, 2014).
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Takai, R., Ohta, T. A commentary on de novo MEIS2 mutation causes syndromic developmental delay with persistent gastro-esophageal reflux. J Hum Genet 61, 773–774 (2016). https://doi.org/10.1038/jhg.2016.81
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DOI: https://doi.org/10.1038/jhg.2016.81
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